Evidence map›Paper›PMID 41385126›Full record

ArticleJournal of autism and developmental disorders2025

Higher Intraindividual Gait Variability in Autistic Toddlers: A Pilot Study.

Joana M Almeida Osório, Baptiste Ulrich-Ischer, Laura F Mendes, Sonia Richetin, Vincent Junod, Borja Rodríguez-Herreros, Anne M Maillard, Julien Favre, Marine Jequier Gygax, Nadia Chabane

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Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Joana M Almeida OsórioAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. Joana.Almeida-Osorio@chuv.ch.ORCID http://orcid.org/0000-0001-9762-8870
Baptiste Ulrich-IscherBioMotion Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-4005-0806
Laura F MendesAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Sonia RichetinAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Vincent JunodAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-7278-6717
Borja Rodríguez-HerrerosAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-9392-7996
Anne M MaillardAutism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-4811-0693
Julien Favre *BioMotion Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-2368-2070
Marine Jequier Gygax *Autism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-1266-6873
Nadia Chabane *Autism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-3187-0178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMotor impairments are pervasive in Autism Spectrum Disorder (ASD), with atypical gait patterns often observed but understudied in early development. The aim of this pilot study was to analyze spatiotemporal gait parameters and variability in toddlers with ASD compared to typically developing (TD) peers.

methodsThe study included 12 ASD and 9 TD male toddlers, aged 18-30 months, walking independently. We extracted spatiotemporal gait parameters from laboratory recordings of walking. Gait variability was assessed via coefficients of variation for each parameter. Group differences were tested and exploratory correlations between gait parameters and motor skills were assessed.

resultsResults indicated increased gait variability in the ASD group across parameters, suggesting less consistent motor control. Significant differences in variability were observed in stride length, step length, stance time, and stride time.

conclusionThis pilot study confirms that an objective assessment of gait is feasible in toddlers with ASD. Future research is needed to replicate the results in a larger sample, to explore underlying neurological mechanisms, as well as the impact of atypical gait maturation on other developmental domains. Early identification of atypical gait patterns could aid in designing interventions targeting motor development, potentially improving broader developmental outcomes in ASD.

Indexed as

Autism spectrum disorder (ASD)Early childhoodGaitIntraindividual variabilityMotor development

Identifiers

PMID41385126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.