Evidence map›Paper›PMID 41384308›Full record

ArticleMolecular medicine reports2026

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis.

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang

Abstract readExpression of Concern
In one paragraph

Article in Molecular medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yi HanDepartment of Traumatology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China.
Xiaoyan WangDepartment of Traumatology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China.
Enqiang MaoDepartment of Emergency, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China.
Boyong ShenDepartment of General Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China.
Liang HuangDepartment of Traumatology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the TUNEL assay experiments shown in Fig. 2E on p. 5, the Merge panels for the shFLVCR1‑AS1 experiments shown for the Caco‑2 and SW480 cell lines appeared to have been inserted into this figure the wrong way around. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 23: 139, 2021; DOI: 10.3892/mmr.2020.11778].

Indexed as

Colorectal NeoplasmsGene Expression Regulation, NeoplasticMicroRNAsReceptors, VirusRNA, Long NoncodingCaco-2 CellsCell Line, TumorCell ProliferationDisease ProgressionHumansMembrane Transport ProteinsFLVCR1 protein, humanMembrane Transport ProteinsMicroRNAsReceptors, VirusRNA, Long Noncodingcolorectal cancerfeline leukemia virus subgroup C receptor 1 antisense RNA 1miR‑381Ras‑related protein 2a

Identifiers

PMID41384308
PMCPMC12715385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.