Evidence map›Paper›PMID 41384306›Full record

ArticleInternational journal of molecular medicine2026

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yiyang Pan *General Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.
Feng Yang *General Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.
Liucan Wang *General Surgery Laboratory, Department of General Surgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, P.R. China.
Tianshu YangGeneral Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.
Guangsheng DuGeneral Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.
Cong XuGeneral Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.
Hua YangGeneral Surgery Laboratory, Department of General Surgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, P.R. China.
Min YuGeneral Surgery Laboratory, Department of General Surgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, P.R. China.
Weidong XiaoGeneral Surgery Laboratory, Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic idiopathic intestinal inflammatory disease with increasing incidence worldwide. However, the treatment of IBD is still limited and has not reached the expected therapeutic effect and new therapeutic targets are still to be discovered. Impaired autophagy and abnormal glycolysis levels were observed both in the

Indexed as

AutophagyGlycolysisInflammatory Bowel DiseasesIntestinal MucosaPhosphofructokinase-2AnimalsFemaleHumansMaleMiceMice, Inbred C57BLPFKFB3 protein, humanPFKFB3 protein, mousePhosphofructokinase-2autophagyglycolysisinflammatory bowel diseasePFKFB3ubiquitination

Identifiers

PMID41384306
PMCPMC12768472

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.