ReviewNeuroprotection (Chichester, England)2023
Liquid-liquid phase separation in synaptopathies.
Review in Neuroprotection (Chichester, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Liquid-liquid phase separation in synaptopathies.Neuroprotection (Chichester, England) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liquid-liquid phase separation has emerged as an important mechanism for regulating cell activity by promoting the formation of membrane-less condensates. In the nervous system, the formation of distinct molecular condensates via phase separation is involved in synaptic assembly and function. Disruption of phase separation is associated with several disease states, such as cancer, neurodegenerative disorders, and neurodevelopmental disorders. This review summarizes the function of phase separation in the assembly and plasticity of the synapse, discusses the role of abnormal phase separation in neurological diseases, and proposes potential treatment options for these neurological diseases based on phase separation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.