ArticleInternational medical case reports journal2025
HIV-Related Toxoplasmosis Infection. A Rare Case of Simultaneous Cardiac and Cerebral Involvement.
Article in International medical case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Toxoplasmosis is a significant opportunistic infection among people living with HIV (PLHIV), primarily manifesting as cerebral disease. Cardiac involvement, while rare, significantly complicates clinical management. This report describes an unusual presentation of concurrent cerebral and cardiac toxoplasmosis in a 50-year-old HIV-positive male initially treated for severe malaria. Despite initial symptomatic relief, the patient rapidly deteriorated neurologically and subsequently succumbed. The autopsy revealed characteristic cerebral and myocardial lesions confirmed by histopathology. The case underscores the diagnostic complexities and the necessity for high clinical suspicion in managing PLHIV with atypical presentations, especially in malaria-endemic areas.
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