Evidence map›Paper›PMID 41384207›Full record

ArticleCureus2025

Initial Institutional Experience and Workflow of Biology-Guided Radiotherapy (BgRT) for a Patient With Non-small Cell Lung Cancer.

Young Suk Kwon, Bin Cai, Chenyang Shen, Thomas I Banks, Rameshwar Prasad, Orhan K Oz, Tu Dan, Aurelie Garant, Kenneth Westover, David Sher and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Young Suk KwonRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Bin CaiRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Chenyang ShenRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Thomas I BanksRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Rameshwar PrasadRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Orhan K OzRadiology, University of Texas, Southwestern Medical Center, Dallas, USA.
Tu DanRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Aurelie GarantRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Kenneth WestoverRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
David SherRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Robert TimmermanRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.
Shahed BadiyanRadiation Oncology, University of Texas, Southwestern Medical Center, Dallas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of a 69-year-old gentleman with a biopsy-proven non-small cell lung cancer (NSCLC) who was treated with the SCINTIX biology-guided radiotherapy (BgRT). In this report, we focus on the development of our institutional clinical workflow for BgRT to ensure a safe and seamless process. This entails the initial import of diagnostic PET/CT with fluorodeoxyglucose-avid lesion(s), 4D CT simulation, contouring including the biology tracking zone, a patient modeling session for planning PET, and radiation treatment (RT). BgRT is a promising technology that has the potential to allow functional adaptation of RT. In our patient with NSCLC who was treated with 5-fraction BgRT, we were able to achieve the threshold for activity concentration and a sufficiently normalized tumor signal. Furthermore, the time analyses of treatment steps demonstrated an efficient workflow.

Indexed as

biology-guided radiotherapy (bgrt)fdglinac-basedpetscintix

Identifiers

PMID41384207
PMCPMC12695321

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.