Evidence map›Paper›PMID 41384175›Full record

ArticleCureus2025

Anterior Quadratus Lumborum Block: A Regional Anaesthetic Technique for the Management of Acute Back Pain in the Emergency Department.

Janam Vadgama, Samia Ahmad, Athmaja Thottungal, Salman Naeem

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janam VadgamaMedicine, King's College Hospital, London, GBR.
Samia AhmadGeneral Practice, Hill Cove Medical Centre, Adelaide, AUS.
Athmaja ThottungalAnaesthesiology, East Kent Hospitals University NHS Foundation Trust, Canterbury, GBR.
Salman NaeemEmergency Department, Flinders Medical Centre, Adelaide, AUS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lower back pain presents a major clinical and economic burden, accounting for substantial emergency department (ED) attendances and significant healthcare utilisation. Quadratus lumborum (QL) syndrome is an under-recognised cause of acute lower back pain, often resistant to standard pharmacological therapy. While ultrasound-guided anterior quadratus lumborum block (AQLB) has demonstrated analgesic efficacy in perioperative settings, its role as a rescue analgesic in the ED remains underexplored. A 49-year-old male presented to the ED with severe bilateral flank pain (numeric rating scale (NRS) = 8/10), radiating to the left leg and groin. This was his second ED presentation in one week. Imaging showed no renal calculus, and laboratory results were largely unremarkable except for mild leukocytosis and chronic kidney disease stage 3. His pain was refractory to multimodal systemic analgesia, including opioids and non-steroidal anti-inflammatory drugs. On review, he was found to have bilateral QL tenderness limiting mobility. Given ongoing severe pain (NRS = 8/10), ultrasound-guided bilateral AQLB was performed using 30 mL of 0.18% ropivacaine on each side with a 21G SonoPlex®II needle (Pajunk®, Geisingen, Germany), accompanied by intravenous dexamethasone (6 mg). Pain scores improved to 2/10 NRS within 30 minutes, allowing mobilisation and discharge within 24 hours on a simple analgesia regimen and physiotherapy advice. Pain recurrence occurred three days later, prompting re-presentation. This case highlights AQLB as a feasible and effective rescue technique for acute back pain in the ED, particularly in patients with QL syndrome who do not respond adequately to systemic analgesics. The rapid and substantial pain reduction post-block suggests a significant role for AQLB in interrupting QL pain-spasm cycles, enabling early mobilisation and reducing hospital admissions. Although systemic analgesia may have contributed, the temporal relationship supports the block's primary effect. Adjuncts such as dexamethasone and gabapentinoids may prolong block duration, though evidence in AQLB for non-operative pain remains limited. Broader adoption of regional anaesthesia in ED practice could improve patient outcomes, decrease opioid use, and optimise healthcare resource utilisation. Future research should focus on standardising the technique, evaluating the duration of effect, and assessing long-term outcomes, including mobility, functional recovery, and healthcare utilisation. This case suggests that AQLB is a feasible and effective opioid-sparing rescue technique for the management of acute back pain in the ED secondary to QL syndrome. It adds to emerging evidence supporting its role as a safe, effective, and resource-efficient intervention, meriting further prospective evaluation.

Indexed as

acute lower back painanterior quadratus lumborum blockemergency medicinequadratus lumborum syndromeregional anaesthesia

Identifiers

PMID41384175
PMCPMC12694938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.