ReviewCureus2025
Time to Avoid Prophylactic Intra-abdominal Drainage in Acute Complicated Appendicitis: An Updated Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review and meta-analysis sought to compare clinical outcomes between patients who received abdominal drains and those who did not following appendicectomy for complicated appendicitis. A search across MEDLINE, PubMed, ScienceDirect, Embase, Scopus, and ClinicalTrials.gov identified 21 studies with 4,930 patients, including 1,809 with drains and 3,121 without. The meta-analysis revealed no significant statistical difference between the two groups regarding post-operative abdominal collection or mortality. The no-drain group yielded better results, with significantly fewer rates of surgical site infection, faecal fistulae, intestinal obstruction, and paralytic ileus, along with a shorter hospital stay. Additionally, a subgroup analysis of paediatric patients indicated an increased risk of abdominal collection in the drain group. Therefore, the evidence suggests that using an abdominal drain in appendectomy for complicated appendicitis increases post-operative complications, lengthens hospital stays, and elevates the risk of abdominal collection in children.
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Registered trials
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