From Black Death to COVID-19: Lessons Learned from the Past Pandemics.

Introduction: Throughout human history, pandemics such as Black Death, Smallpox, Spanish Flu and COVID-19 caused global outbreaks and spread of infectious pathogens resulting in significant morbidity and mortality. They also had profound social, cultural, political and economic effects. Various public health containment measures and treatment strategies were implemented in response to the outbreaks. Societal responses to the pandemics and the recommended control measures, though variable, followed common central themes over the centuries. Some of common themes included blaming outsiders or marginalized communities for the spread of diseases, defiance of public health measures, demands for change through social unrest, the spread of misinformation about diseases and unproven treatments, and complaints about healthcare disparities and socioeconomic inequalities. Methods: Literature reviews were conducted via academic search engines Medline, Google Scholar, Web of Science and to identify pertinent historical and modern research and review articles related to the topic. Results: The paper reviews the historical significance of the four pandemics, their pathophysiology, the public health strategies against the infectious agents and the psychosocial impacts of the outbreaks. The findings suggest that successful response to pandemic recurrences is not only driven by scientific advancements and government mandates but is also dependent on societal behavior and reactions as well as community environments and social determinants of health. Discussion: Throughout previous pandemics, valuable lessons were overlooked, and little attention was placed on psychosocial factors. Understanding societal behaviors, human nature, disparities in socioeconomic status and inequalities can have a profound impact in combating the next pandemic.