ArticleFrontiers in medicine2025
Efficacy of the silicone rubber uterine stent in the prevention of adhesion after hysteroscopic adhesiolysis: a prospective, randomized, controlled trial.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Background: Recurrent intrauterine adhesions (IUAs) after hysteroscopic adhesiolysis severely compromise fertility. This randomized trial investigated the efficacy of a pioneering silicone rubber uterine stent in preventing adhesion reformation. Methods: In a single-center, double-blind trial, 45 patients with moderate-to-severe IUAs underwent hysteroscopic adhesiolysis. The patients were randomized to receive a silicone rubber uterine stent (treatment group) or an auto-crosslinked hyaluronic acid gel. Intrauterine device (IUD) and 12-f Foley balloon catheter at the end of surgery (control group). All patients underwent second-look hysteroscopy at 2-3 months and hormonal therapy for two cycles after surgery. Pregnancies over 5 years were followed up. Results: Both groups had reduced American Fertility Society (AFS) scores postoperatively ( Conclusion: Silicone uterine stents represent a breakthrough in preventing post-adhesiolysis IUAs, particularly for severe cases, offering enhanced anatomical recovery and fertility outcomes. This innovation addresses a critical unmet need in reproductive surgery, providing a robust strategy to safeguard fertility potential.
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