ReviewRSC advances2025
Nanoliposome-based drug delivery systems for the treatment of diabetes mellitus: a review.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Icariin-loaded liposomal nanoparticles alleviate streptozotocin-induced diabetic hepatopathy associated with modulation of ferroptosis-related and inflammatory signaling.BMC pharmacology & toxicology · 2026Article
- Glucose-Responsive Nanomedicine in Diabetes Therapy: Emerging Advances and Clinical Prospects.Journal of functional biomaterials · 2026Review
- Article
- Liposomal honokiol attenuates dimethylhydrazine-induced colon carcinogenesis in rats through modulation of oxidative stress, inflammation, apoptosis, autophagy, and lipid metabolism pathways.Medical oncology (Northwood, London, England) · 2026Article
- Advances in Nano-Drug Delivery Systems for Chronic Autoimmune Diseases: A Focus on Diabetes Mellitus, Inflammatory Bowel Disease, and Rheumatoid Arthritis.Molecules (Basel, Switzerland) · 2026Review
- Advances in the application of nanoparticles for the diagnosis and treatment of diabetic cardiomyopathy.Frontiers in cell and developmental biology · 2026Review
- Editorial: Pharmacological advancements of novel natural-based nanomedicines.Frontiers in pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus (DM) is one of the leading world health complications, with chronic hyperglycemia that is due to a lack of insulin production or insulin action. Although many pharmacological agents are available, the current treatment modality is hampered by low bioavailability, rapid drug clearance, frequent dosing, and adverse effects. Such difficulties have been especially pronounced in the treatment of type 1 and type 2 diabetes, where long-term glycemic control that does not undermine patient compliance has been hard to reach. Nanotechnology has become one of the most revolutionary tools in drug delivery to achieve targeted, sustained, and more effective therapeutic outcomes in the past few years. Nanoliposomes are nanoscale vesicles formed from lipid bilayers and have exhibited remarkable potential due to their biocompatibility, ability to host both hydrophilic and lipophilic drugs, and controlled release. Nanoliposomes have the potential of improving solubility of drugs, protect therapeutic agents against enzyme activities, and produce a controlled drug release, which offers a new possibility in the treatment of diabetes. In addition to glucose-lowering, targeted liposomal treatment approaches combat major complications, such as cardiomyopathy, nephropathy, and retinopathy, through increased myocardial protection, renal resilience, and ocular drug exposure. This review provides a thorough overview of the progress, formulation methods, and therapeutic value of nanoliposomal-based delivery systems targeting antidiabetic drugs. It also focuses on the recent trend in research, the challenges of clinical translation, and the future of nanoliposomes as a paradigm-altering platform in the treatment of diabetes mellitus.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.