Evidence map›Paper›PMID 41384035›Full record

ArticleOrganometallics2025

Combined Metal-Metal and Metal-Ligand Cooperativity in Dicopper-Catalyzed Azide-Alkyne Cycloaddition Reactions.

Cody B van Beek, Hyoju Choi, Marije L A Hilberts, Marijn M Lammertink, Bohyun Park, Martin Lutz, Mu-Hyun Baik, Daniël L J Broere

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In one paragraph

Article in Organometallics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cody B van BeekOrganic Chemistry and Catalysis, Institute for Sustainable Chemistry and Catalysis, Faculty of Science, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
Hyoju ChoiDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-9541-9266
Marije L A HilbertsOrganic Chemistry and Catalysis, Institute for Sustainable Chemistry and Catalysis, Faculty of Science, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
Marijn M LammertinkOrganic Chemistry and Catalysis, Institute for Sustainable Chemistry and Catalysis, Faculty of Science, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
Bohyun ParkCenter for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-0552-8763
Martin LutzStructural Biochemistry, Bijvoet Centre for Biomolecular Research, Faculty of Science, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.ORCID https://orcid.org/0000-0003-1524-9629
Mu-Hyun BaikDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-8832-8187
Daniël L J BroereOrganic Chemistry and Catalysis, Institute for Sustainable Chemistry and Catalysis, Faculty of Science, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.ORCID https://orcid.org/0000-0002-6641-4092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanism of the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction has been under investigation for over two decades. While catalytically relevant dicopper intermediates have been proposed and a few suspected intermediates have been isolated, the mechanism remains poorly understood. In this work, we describe the synthesis and characterization of neutral dicopper complexes bearing the proton-responsive dinucleating

Identifiers

PMID41384035
PMCPMC12690585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.