ArticleFrontiers in psychiatry2025
The mechanism of social interaction deficits in attention-deficit/hyperactivity disorder children: the role of cognitive flexibility.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent mental disorders among children in China. Although the relationship between ADHD symptoms and social interaction deficits has been empirically examined, cognitive flexibility (CF), as a core factor theoretically contributing to ADHD, has still been less studied. Aim: This study aims to explore how CF influences social interaction deficits using both tradition method (questionnaire surveys) and novel paradigms (Reinforcement learning). Method: In study 1, we recruited 20 clinically urban Chinese children diagnosed with ADHD ( Results: Study1 showed that CF mediated the relationship between ADHD symptoms and social interaction deficits in children with ADHD. Study 2 demonstrated that the control group employed both model-based and model-free cognitive strategies; however, the ADHD group did not demonstrate either strategy. These findings indicate a significant difference in CF between ADHD and control groups, particularly in their selection of cognitive strategies. Conclusion: To sum up, the findings suggest that a low level or deficiency in CF may be a key factor contributing to social problems in children with ADHD. Future research directions are further discussed.
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