ArticleFrontiers in veterinary science2025
Resistance evolution under potentiated sulphonamide pressure in
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sulfonamide resistance as a global one health challenge.The Journal of antibiotics · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Antimicrobial resistance (AMR) poses an escalating global health threat. Potentiated sulphonamides are widely used in both veterinary and human medicine. This study aimed to investigate the Methods: The MEGA-plate evolutionary model was used to expose Results: In strains adapted to 1000 × potentiated sulphonamide, MIC values significantly increased for most tested antibiotics. Mutations were identified in key folate pathway genes ( Discussion: These findings underscore the need for cautious use of combination antimicrobials, as they may elicit pleiotropic resistance responses beyond their intended targets.
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Registered trials
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