Evidence map›Paper›PMID 41383857›Full record

ReviewInternational journal of dentistry2025

Concentrated Growth Factors and Bone Grafting in Maxillary Sinus Lift: A Systematic Review.

Antonio Mancini, Francesco Inchingolo, Angelo Michele Inchingolo, Vincenzo Carpentiere, Gaetano Del Vecchio, Andrea Palermo, Alessio Danilo Inchingolo, Gianna Dipalma

Abstract readReview
In one paragraph

Review in International journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonio ManciniDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.
Francesco InchingoloDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.ORCID https://orcid.org/0000-0003-3797-5883
Angelo Michele InchingoloDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.
Vincenzo CarpentiereDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.ORCID https://orcid.org/0000-0002-3579-7342
Gaetano Del VecchioDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.
Andrea PalermoUniversity of Salento, Lecce 73100, Italy.
Alessio Danilo InchingoloDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.
Gianna DipalmaDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari 70124, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This review evaluates the latest studies on the effectiveness of growth factor concentrates and bone grafts (BGs) in maxillary sinus lift (MSL) procedures, emphasizing their role in bone regeneration and healing. The aim is to determine their impact on enhancing clinical outcomes by improving bone quality and accelerating the healing process. Materials and Methods: A comprehensive literature search was conducted using the Scopus, Web of Science, and PubMed databases. The following keywords were employed: "PRP," "L-PRF," "CGF," "oral surgery," and "sinus lift," combined with the Boolean operators "AND" and "OR." A total of 727 studies were initially identified, of which 18 met the inclusion criteria for this review. Results: The included studies demonstrate that the use of growth factors in conjunction with alloplastic and xenogeneic BGs significantly promotes early vascularization and has potent proangiogenic effects in vivo. Furthermore, these combinations reduce postoperative inflammation and discomfort, accelerating the healing process and enhancing tissue regeneration. Conclusions: Although further research is necessary, current evidence suggests that autologous platelet concentrates hold promise for improving clinical outcomes in MSL procedures. They may enhance bone height and thickness, improve vascularization, and expedite postoperative healing, offering a valuable adjunct to traditional bone grafting techniques in oral surgery.

Indexed as

allograftgrowth factor (GF)sinus lift (SL)surgery

Identifiers

PMID41383857
PMCPMC12695408

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.