Evidence map›Paper›PMID 41383812›Full record

ArticleEndoscopy international open2025

Clinical feasibility of gastric endoscopic submucosal dissection in patients on glucocorticoids or immunomodulators: Propensity-score-matched study.

Hiroki Fukuya, Eikichi Ihara, Yoichiro Iboshi, Yorinobu Sumida, Daisuke Yoshimura, Shohei Hamada, Taisuke Sasaki, Akito Ohkubo, Shuichi Itonaga, Hitoshi Homma and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Endoscopy international open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Comment on the study by Fukuya et al. (2025).Endoscopy international open · 2026
    Article
  2. Article
  3. Reply to Sah et al.Endoscopy international open · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Hiroki FukuyaDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Eikichi IharaDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yoichiro IboshiDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Yorinobu SumidaDepartment of Gastroenterology, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
Daisuke YoshimuraDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Shohei HamadaDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Taisuke SasakiDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Akito OhkuboDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Shuichi ItonagaDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Hitoshi HommaDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Ryota OkitsuDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.
Akihisa OhnoFaculty of Medicine, Graduate School of Medical Sciences, School of Medicine, Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan.
Mitsuru EsakiFaculty of Medicine, Graduate School of Medical Sciences, School of Medicine, Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan.ORCID 0000-0001-7353-2153
Naohiko HaradaDepartment of Gastroenterology, National Hospital Organisation Kyushu Medical Center, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Evidence on gastric endoscopic submucosal dissection (ESD) under glucocorticoids or immunomodulators (GC/IM) is limited. We evaluated whether GC/IM use affects gastric ESD outcomes. Patients and methods: We retrospectively analyzed 411 consecutive ESDs (April 2017-April 2022). GC/IM users (n = 32) were compared with controls (n = 379); 1:3 propensity-score matching yielded 27 vs 81 patients. The primary outcome was overall complications, defined as a composite of pain, fever, delayed bleeding, and delayed perforation. Secondary outcomes were each component, intra-procedure perforation, hospital stay, and use of symptom-directed treatments (analgesics, antipyretics, antibiotics). Results: Overall complications were more frequent with GC/IM than controls (44.4% vs 21.0%; Conclusions: In patients receiving GC/IM, gastric ESD was associated with a higher incidence of minor, clinically managed events-chiefly pain and transient fever-whereas major complications remained uncommon. With close monitoring and prompt symptom-directed care, gastric ESD appeared clinically feasible, albeit with slightly greater resource use and observation time.

Indexed as

Endoscopic resection (ESD, EMRc, ...)Endoscopic ultrasonographyEndoscopy Upper GI TractGastric cancerPerformance and complicationsQuality and logistical aspects

Identifiers

PMID41383812
PMCPMC12690568

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.