Case Report: Hypertrophic cardiomyopathy meets left ventricular hypertrabeculation: from mixed cardiomyopathy to hypertrophic cardiomyopathy with hypertrabeculation.

Yang Li, Yang Liu, Xiaofei Zheng, Lijuan Chen, Qiming Dai, Genshan Ma

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In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Yang LiDepartment of Cardiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Yang LiuDepartment of Cardiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Xiaofei ZhengDepartment of Radiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Lijuan ChenDepartment of Cardiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Qiming DaiDepartment of Cardiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Genshan MaDepartment of Cardiology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a young male patient admitted due to worsening of heart failure with recurrent embolic events. He had previously been diagnosed with hypertrophic cardiomyopathy (HCM) and left ventricular systolic dysfunction at other hospitals and was treated irregularly with medications including a beta-blocker and diuretics. On this admission, echocardiography and cardiac MR examination revealed left ventricular myocardial non-compaction combined with HCM. The coexistence of left ventricular hypertrophy and hypertrabeculation is rare, and the diagnosis has been updated according to the newly issued European Society of Cardiology guidelines. The present report describes the clinical features, therapy, and outcome of this disease.

Indexed as

cardiac MRcardiomyopathyheart failurehypertrophic cardiomyopathyleft ventricular non-compaction/hypertrabeculation

Identifiers

PMID41383647

DOI10.3389/fcvm.2025.1708374

PMCPMC12689530

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