Evidence map›Paper›PMID 41383603›Full record

ArticleFrontiers in immunology2025

A novel TNFR2 agonist peptide for the expansion of CD4+Foxp3+ regulatory T cells.

Ping Liao, Zhonghao Chen, Yang Gao, Yang Yang, Yibo Chen, Jiamin Chen, Yiru Wang, Chon-Kit Chou, Shaoyi Zhang, Xin Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ping Liao *Institute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Zhonghao Chen *Institute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Yang Gao *Institute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Yang YangInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Yibo ChenInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Jiamin ChenInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Yiru WangInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Chon-Kit ChouInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Shaoyi ZhangInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.
Xin ChenInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Taipa, Macau SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

PeptidesReceptors, Tumor Necrosis Factor, Type IIT-Lymphocytes, RegulatoryAnimalsCell ProliferationCytokinesForkhead Transcription FactorsHumansLymphocyte ActivationMiceMice, Inbred C57BLSignal TransductionCytokinesForkhead Transcription FactorsFOXP3 protein, humanPeptidesReceptors, Tumor Necrosis Factor, Type IITNFRSF1B protein, humanCD4+Foxp3+ regulatory T cellsimmunosuppressioninflammationpeptideTNFR2

Identifiers

PMID41383603
PMCPMC12689330

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.