ReviewFrontiers in surgery2025
Impact of individualized and structured aerobic exercise on clinical outcomes in pediatric congenital heart diseases with post-surgical rehabilitation: a meta-analysis.
Review in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Determinants and Implementation of Hybrid Cardiac Rehabilitation in Adolescents and Young Adults With Congenital Heart Disease: Insight From the QUALIREHAB Study.Journal of the American Heart Association · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Children with congenital heart defects (CHD) commonly experience decreased exercise capacity due to structural heart abnormalities, surgical interventions, and parental-and physician-imposed activity restrictions. This reduced activity can lead to physical deconditioning, impaired quality of life, and increased cardiovascular risk later in life. While exercise-based rehabilitation is highly recommended, significant knowledge gaps persist regarding the long-term impact of structured exercise on diverse CHD subtypes, optimal modalities, and standardized protocols for implementation. This meta-analysis assesses the effect of structured exercise rehabilitation programs on functional and health-related outcomes in children with CHD. Methods: A comprehensive search was done using PubMed/MEDLINE, Embase, and Web of Science until April 23, 2025, for randomized controlled trials (RCTs) and observational studies which compares exercise or cardiac rehabilitation with standard of care or no rehabilitation intervention in pediatric CHD patients. Key outcomes included changes in exercise duration, peak oxygen uptake (peak VO2), peak workload, heart rate, and other cardiopulmonary parameters. Data were analyzed and pooled using random-effects models, with heterogeneity evaluated via I Results: Ten studies (5 RCTs, 5 observational) comprising of 378 patients were included. Exercise rehabilitation significantly elevated exercise duration [MD = 0.55, 95% CI: (0.01, 1.09); Conclusion: Exercise rehabilitation moderately enhances exercise duration in pediatric CHD patients but does not notably enhance most cardiopulmonary parameters. High heterogeneity reflects outcomes variability by CHD subtype and intervention protocol. Standardized, multicenter trials are required to improve and optimise exercise prescriptions and evaluate long-term benefits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.