Evidence map›Paper›PMID 41383512›Full record

ArticleFrontiers in oncology2025

Wernicke's encephalopathy in a patient with adenoid cystic carcinoma: case report and literature review.

Ioannis Kotsantis, Anna Boulouta, Panagiota Economopoulou, Anastasios Kyriazoglou, Sotirios Karamagkiolas, Maria Kyrkasiadou, Niki Gavrielatou, Maria Anastasiou, Anastasios Pantazopoulos, Amanda Psyrri

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ioannis Kotsantis *Second Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Anna Boulouta *Second Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Panagiota EconomopoulouSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Anastasios KyriazoglouSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Sotirios KaramagkiolasSecond Otolaryngology Department, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Maria KyrkasiadouSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Niki GavrielatouSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Maria AnastasiouSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Anastasios PantazopoulosSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Amanda PsyrriSecond Department of Internal Medicine, Oncology Unit, Attikon University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wernicke's encephalopathy is an acute neurologic disorder caused by thiamine (vitamin B1) deficiency, which is most commonly associated with alcoholism. Rare cases of Wernicke's encephalopathy have been described in cancer patients, mostly with gastrointestinal and hematologic malignancies. Head and neck cancer patients frequently have reduced oral intake as a direct result of their tumor or from chemoradiation treatments. We report a case of Wernicke's encephalopathy in a 44-year-old woman with adenoid cystic carcinoma following chemoradiotherapy. Through a literature review we identified additional cases of Wernicke's encephalopathy in head and neck cancer patients, highlighting the importance of recognizing nutritional deficiencies and associated complications. The findings emphasize the need for heightened awareness regarding the risk of thiamine deficiency in cancer patients, particularly those experiencing poor nutritional intake due to treatment-related side effects. Prompt diagnosis and intervention are critical to prevent serious morbidity and mortality associated with this condition.

Indexed as

adenoid cystic carcinomahead & neck cancerHNSCCneurological manifestationnutritional complicationsthiamine deficiencyWernicke’s encephalopathy

Identifiers

PMID41383512
PMCPMC12689301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.