Evidence map›Paper›PMID 41383507›Full record

ArticleFrontiers in oncology2025

Dual malignancies: a case report of the sequential occurrence of a trichilemmal tumor and breast carcinoma in a 56-year-old female.

Bhargav Vuppumalla, A Ravichandran, M Manickavasagam, Chaitanya Kumar Javvaji, Keta Vagha

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhargav Vuppumalla *Department of Medical Oncology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
A RavichandranDepartment of Medical Oncology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
M ManickavasagamDepartment of Medical Oncology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Chaitanya Kumar Javvaji *Department of Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, India.
Keta VaghaDepartment of Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors present a rare case of the sequential occurrence of a malignant trichilemmal tumor (MPTT) and invasive ductal carcinoma of the breast in a 56-year-old woman. The patient initially presented with a palpable breast lump and a longstanding asymptomatic scalp swelling that had been present since childhood. Histopathological evaluation confirmed the breast lump as invasive ductal carcinoma, while the scalp swelling, initially suspected to be a benign cyst, was diagnosed as an MPTT. The patient underwent combination chemotherapy, which resulted in a favorable response of the breast carcinoma; however, the MPTT exhibited a discordant therapeutic outcome. Trichilemmal carcinoma is an uncommon cutaneous neoplasm, and its coexistence with breast carcinoma represents an exceedingly rare clinical scenario. Furthermore, the differential response of these malignancies to chemotherapy presents a significant therapeutic challenge. This case underscores the importance of accurate diagnosis, individualized treatment strategies, and a multidisciplinary approach for optimally managing such complex oncological presentations.

Indexed as

breast carcinomachemotherapydiscordant responseductal carcinomatargeted therapytrichilemmal tumour

Identifiers

PMID41383507
PMCPMC12689299

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