Evidence map›Paper›PMID 41383497›Full record

ArticleFrontiers in oncology2025

Intra-voxel incoherent motion biomarker repeatability in healthy volunteers and sensitivity to chemoradiotherapy-induced changes in patients with uterine cervical cancer.

Damien J McHugh, Anubhav Datta, Michael J Dubec, David L Buckley, Ross A Little, Michael Berks, Susan Cheung, Kate Haslett, Lisa Barraclough, Catharine M L West and 3 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Damien J McHugh *Christie Medical Physics and Engineering, The Christie National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
Anubhav Datta *Division of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Michael J DubecChristie Medical Physics and Engineering, The Christie National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
David L BuckleyChristie Medical Physics and Engineering, The Christie National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
Ross A LittleDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Michael BerksDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Susan CheungDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Kate HaslettClinical Oncology, The Christie National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
Lisa BarracloughClinical Oncology, The Christie National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
Catharine M L WestDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Ananya ChoudhuryDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
Peter HoskinDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.
James P B O'ConnorDivision of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intra-voxel incoherent motion (IVIM) biomarkers require validation for translation into clinical practice. This work evaluates repeatability and sensitivity to treatment of IVIM biomarkers in the uterine cervix, and assesses suitability of the IVIM model. Six healthy volunteers underwent two scans to evaluate repeatability. Eight patients with stage IIB-IVA cervical squamous cell carcinoma were scanned pre-treatment, and at weeks 3 and 5 into treatment. IVIM and apparent diffusion coefficient (ADC) model fits were compared using the corrected Akaike information criterion (AIC

Indexed as

biomarkersdiffusion magnetic resonance imagingimage processingintra-voxel incoherent motionmodel comparisonradiotherapyuterine cervical neoplasms

Identifiers

PMID41383497
PMCPMC12689363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.