Evidence map›Paper›PMID 41383486›Full record

ArticleBladder cancer (Amsterdam, Netherlands)

Impact of neighborhood deprivation on bladder cancer outcomes: A regional analysis.

Anosh Dadabhoy, Chirag Doshi, Mazyar Zahir, Farshad Sheybaee Moghaddam, Luis Santos Molina, Sejal Mehta, Erika L Wood, Leilei Xia, Gus Miranda, Jie Cai and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bladder cancer (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anosh DadabhoyDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0009-0003-1578-4901
Chirag DoshiDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-0878-3559
Mazyar ZahirDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-6574-3919
Farshad Sheybaee MoghaddamDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Luis Santos MolinaDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Sejal MehtaDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Erika L WoodDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Leilei XiaDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Gus MirandaDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Jie CaiDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Hooman DjaladatDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Anne SchuckmanDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Siamak DaneshmandDepartment of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neighborhood Deprivation (ND) indices serve as indicators of socioeconomic status and are recognized determinant of survival across multiple cancer types. Objective: To determine the potential effect of ND on urothelial bladder cancer survival outcomes using a California-specific measure, the Healthy Places Index (HPI). Methods: We queried our institutional database for patients who underwent radical cystectomy from 2013 to 2019. Patients were categorized into HPI quartiles based on their residential areas, with Q1 representing the most disadvantaged and Q4 the least disadvantaged. Multivariable logistic regression was used to identify predictors of adverse pathological features. Multivariable cox regression was utilized to evaluate the association of HPI with overall survival (OS) and recurrence free survival (RFS). Results: A total of 729 patients were included in our analysis. Belonging to the most disadvantaged quartile (Q1) was associated with higher odds of lymphovascular invasion (HR 1.94, Conclusions: Greater ND is associated with adverse pathology on presentation and worse OS following radical cystectomy for UBC. Larger prospective studies are warranted to further assess the influence of social disparities on survival outcomes following RC.

Indexed as

socioeconomic factorssurvival analysistreatment outcomeurinary bladder neoplasms

Identifiers

PMID41383486
PMCPMC12690065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.