Evidence map›Paper›PMID 41383355›Full record

ArticleDEN open2026

Enhanced Visualization of the Distal Myotomy Endpoint during Peroral Endoscopic Myotomy Using Indocyanine Green With Infrared Imaging.

Yuichiro Ikebuchi, Takuki Sakaguchi, Moe Eizawa, Tsuyoshi Mikamo, Kazuhiro Takemoto, Yuki Fujii, Ryohei Ogihara, Yu Kamitani, Mirai Edano, Hidehito Kinoshita and 5 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuichiro IkebuchiDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.ORCID https://orcid.org/0000-0003-1672-8584
Takuki SakaguchiDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Moe EizawaDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Tsuyoshi MikamoDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Kazuhiro TakemotoDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Yuki FujiiDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Ryohei OgiharaDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Yu KamitaniDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Mirai EdanoDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Hidehito KinoshitaDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Hiroki KurumiDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Takashi HasegawaDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Koichiro KawaguchiDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Kazuo YashimaDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.
Hajime IsomotoDepartment of Multidisciplinary Internal Medicine Division of Gastroenterology and Nephrology Tottori University Hospital Tottori Japan.ORCID https://orcid.org/0000-0001-8998-7865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peroral endoscopic myotomy (POEM) is an effective treatment for achalasia; however, accurately identifying the distal extent of myotomy remains a technical challenge. Indocyanine green with infrared imaging (ICG-IRI) may facilitate the intraoperative visualization of the esophagogastric junction. Methods: We evaluated 39 patients who underwent POEM using ICG-IRI. The primary outcome was the success rate of ICG-IRI, defined as a clear endoscopic visualization of fluorescence at the distal myotomy endpoint. The secondary outcomes included technical success, changes in integrated relaxation pressure, and Eckardt scores before and after treatment. Results: The technical success rate was 100%, and ICG-IRI was successful in 94.9% of the cases (37/39). The median integrated relaxation pressure decreased from 26.9 to 10.8 mmHg, and the median Eckardt score improved from 5.0 to 1.0 (both Conclusions: The ICG-IRI method is a reliable visual aid for identifying distal myotomy endpoints during POEM. This technique may enhance the procedural accuracy and improve clinical outcomes.

Indexed as

esophageal achalasiaesophageal motility disordersesophagusindocyanine greenmyotomy

Identifiers

PMID41383355
PMCPMC12693724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.