ArticleFrontiers in public health2025
Multimorbidity patterns and cognitive frailty in adults aged over 50 years: China perspective.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cognitive frailty risk prediction models in patients with chronic kidney disease in China: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Mild cognitive impairment and pre-frailty show distinct plasma multi-omic signatures: a cross-sectional study.GeroScience · 2026Article
- Dual decline in gait and cognition as a high-risk clinical phenotype: differential associations with cerebral amyloid-Frontiers in aging neuroscience · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The multimorbidity underlying in cognitive frailty remain poorly understood. Methods: A cross-sectional study was performed in non-dementia Chinese aged over 50 years, Cognitive frailty (cognitive impairment and slow gait [SG]). Cardiovascular and cerebrovascular diseases (CCVD) (heart disease, type 2 diabetes, hypertension, hyperlipidemia and cerebral infarction). Continuous variables were evaluated using one-way analysis of variance (ANOVA). Categorical variables were assessed using the chi-square test. Pairwise comparisons were performed using the Bonferroni-corrected column proportion test (z-test). Multiple logistic regression analysis was conducted to identify factors associated with cognitive frailty. Results: A cross-sectional study included 571 males and 1,182 non-demented Chinese aged ≥50 years, categorized into 6 groups: normal, SG, subjective cognitive decline alone (SCD-A), mild cognitive impairment alone (MCI-A), subjective cognitive decline with slow gait (SCD-SG), and mild cognitive impairment with slow gait (MCI-SG). Cognitive frailty was defined as cognitive impairment plus SG. Walking speed and hand grip strength were lower in SG, SCD-SG, and MCI-SG groups ( Conclusion: Cognitive frailty in Chinese aged ≥50 years increases risk of ≥3 chronic diseases, with SCD-SG group at highest risk, highlighting the need for attention to cognitive frailty and multimorbidity.
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