Evidence map›Paper›PMID 41383325›Full record

ArticleFrontiers in public health2025

Outcomes of a tribal community program on hepatitis C, HIV, and syphilis screening, confirmation testing, and treatment initiation for an underserved population.

Ashley Comiford, Jorge Mera, Kendra Lewis, Savana Christy, Molly Feder, Andrea Blair

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashley Comiford *Department of Infectious Diseases, Cherokee Nation Outpatient Health Center, Cherokee Nation Health Services, Tahlequah, OK, United States.
Jorge Mera *Department of Infectious Diseases, Cherokee Nation Outpatient Health Center, Cherokee Nation Health Services, Tahlequah, OK, United States.
Kendra LewisDepartment of Infectious Diseases, Cherokee Nation Outpatient Health Center, Cherokee Nation Health Services, Tahlequah, OK, United States.
Savana ChristyDepartment of Infectious Diseases, Cherokee Nation Outpatient Health Center, Cherokee Nation Health Services, Tahlequah, OK, United States.
Molly FederSea Glass Group, Seattle, WA, United States.
Andrea BlairDepartment of Infectious Diseases, Cherokee Nation Outpatient Health Center, Cherokee Nation Health Services, Tahlequah, OK, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: American Indian and Alaska Native people are disproportionately impacted by hepatitis C, HIV, and syphilis, with rates 2.3, 1.9, and 6.4 times that of non-Hispanic White people, respectively. The objective was to describe the first 9 months implementing a community-based tribal program to screen and link underserved people to hepatitis C, HIV, and syphilis care and treatment. An additional objective was to identify patient characteristics associated with completing confirmation testing when indicated. Methods: This study occurred from January through September 2024 on the Cherokee Nation reservation in Oklahoma. Survey and medical record data from Cherokee Nation's Hepatitis C Engagement and Linkage Program, a collaboration between the Cherokee Nation Health Services and community programs servicing people with substance use disorders and/or reduced healthcare access. People 18 years and older who visited the organizations during the project period and provided consent were eligible. Project outcomes, including point of care screening results, receipt of confirmation testing, test results, and treatment initiation, were assessed using counts and proportions. Associations between patient characteristics and completion of confirmation testing were assessed using Chi-square or Fisher's exact tests. Results: The program screened 503 people, including 365 American Indian and Alaska Native people, for hepatitis C, HIV, and syphilis. Forty-five percent of participants reported lifetime injection drug use. Overall, 102 (20%) participants had a reactive hepatitis C antibody test, 36 (35%) of whom received confirmatory hepatitis C RNA testing. Sixteen people were diagnosed with hepatitis C infection, 12 (75%) of whom initiated treatment. Sixty participants (12%) had a reactive Conclusion: Cherokee Nation successfully screened underserved individuals for hepatitis C, HIV, and syphilis with moderate success in further evaluation and treatment. Future interventions should include onsite treatment options to prevent barriers to accessing healthcare.

Indexed as

Hepatitis CHIV InfectionsMass ScreeningSyphilisVulnerable PopulationsAdultAmerican Indian or Alaska NativeFemaleHumansMaleMiddle AgedOklahomaAlaska NativeAmerican Indiancommunity settinghepatitis Cscreening

Identifiers

PMID41383325
PMCPMC12689552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.