Evidence map›Paper›PMID 41383318›Full record

ArticleFrontiers in public health2025

Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.

Xintong Chen, Yongxin Tong, Jun Wang

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xintong ChenInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, China.
Yongxin TongInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, China.
Jun WangInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The growing use of disinfectants has raised ecological concerns regarding disinfectants as emerging environmental contaminants. Given the similarities in environmental fate and discharge behavior between pharmaceuticals and disinfectants, ecopharmacovigilance (EPV) as a framework emphasizing eco-directed pharmaceutical use and disposal was previously proposed as a potential strategy to mitigate environmental emissions of disinfectants. This study investigated the likelihood of spillover between eco-directed pharmaceutical disposal and pro-environmental disinfectant use across knowledge, attitude, and practice (KAP) dimensions, and examine whether perceived similarity between pharmaceuticals and disinfectants mediated these spillover effects. Methods: Using a sample of 1,002 Chinese residents, questionnaire-based KAP survey data were analyzed using regression analysis for spillover effect test. A bias-corrected non-parametric percentile Bootstrap test was employed to examine mediation effects. Results: A one-unit increase in eco-directed pharmaceutical disposal improved the residents' pro-environmental disinfectant use by 0.648, 0.782, and 0.791 units in KAP dimensions ( Conclusion: Eco-directed pharmaceutical disposal might positively spill over to pro-environmental disinfectant use partially through indirect path of the perceived similarity, which further supports the feasibility of adopting EPV, a framework originally designed for pharmaceutical environmental risk management, for the remediation of disinfectant emerging contaminants.

Indexed as

DisinfectantsHealth Knowledge, Attitudes, PracticeAdultChinaEast Asian PeopleFemaleHumansMaleMiddle AgedPharmaceutical PreparationsSurveys and QuestionnairesDisinfectantsPharmaceutical Preparationsdisinfectionecopharmacovigilanceemerging contaminantsenvironmental spilloverknowledge-attitude-practicepharmaceutical emerging contaminants

Identifiers

PMID41383318
PMCPMC12689939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.