Evidence map›Paper›PMID 41383293›Full record

ArticleGlobal advances in integrative medicine and health

Mindfulness-Based Cognitive Therapy for Depression, Taking It Further (MBCT-D-TiF): An Assessment of an Intervention Development Study.

Chelsea J Siwik, Jessica M Harrison, Willem Kuyken, Zindel Segal, Patricia J Moran, Jennifer N Felder, Wendy Hartogensis, Veronica Goldman, Stuart Eisendrath, Frederick M Hecht and 1 more

Abstract read
In one paragraph

Article in Global advances in integrative medicine and health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chelsea J SiwikDepartment of Wellness and Preventative Medicine, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0003-1417-8582
Jessica M HarrisonOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.
Willem KuykenDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-8596-5252
Zindel SegalDepartment of Psychological Clinical Science, University of Toronto, Scarborough, Toronto, ON, Canada.
Patricia J MoranOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.
Jennifer N FelderOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-4598-7836
Wendy HartogensisOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.
Veronica GoldmanOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.
Stuart EisendrathDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Frederick M HechtOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-5782-1171
Shelley R AdlerOsher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.

Funding

Training Researchers in Clinical Integrative Medicine (TRIM) - NOSI supplementT32AT003997 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHELLEY R ADLER, MARIA T CHAO · 2007 to 2026
$6.6M
A Daily, Digital Mindfulness-Based Intervention for Depressive Symptoms After Serious IllnessK23AT012484 · NCCIH · CLEVELAND CLINIC LERNER COM-CWRU · PI Chelsea Jane Siwik · 2025 to 2026
$406k
NCCIH NIH HHS K23 AT012484NCCIH NIH HHS L30 AT011624NCCIH NIH HHS T32 AT003997
6 · The paper itself

Abstract

Background: Mindfulness-Based Cognitive Therapy (MBCT) reduces depression relapse, yet graduates have expressed a need for structured guidance post-program to maintain mindfulness practice and sustain benefits. To address this, we created MBCT for Depression-Taking it Further (MBCT-D-TiF). Objective: To refine and pilot test feasibility and acceptability of MBCT-D-TiF. Methods: We collected qualitative focus group data to inform refinements and quantitative data to pilot test feasibility and acceptability of MBCT-D-TiF. In round one, participants received MBCT-D-TiF (n = 14), consisting of 4 weekly and then monthly sessions delivered via group videoconferencing. In round two (n = 20), participants were randomized 1:1 to MBCT-D-TiF or waitlist control. Surveys were completed at baseline, 1 and 4 months by all participants. We explored participants' experiences with MBCT-D-TiF in two focus groups (n = 7 in each) conducted via videoconferencing. We used descriptive statistics and mixed linear models to analyze quantitative data and thematic content analysis to analyze qualitative data. Results: MBCT-D-TiF participants (n = 25) attended all weekly sessions (100%) and at least 75% of the monthly sessions (76%); found the weekly sessions very or extremely helpful (77.1%), and the monthly sessions very or extremely helpful (66.7%). The following themes emerged: (1) the importance of the group for participants' social connection, support, and practice community that enhanced their meditative experience, helped improve their mental health, and facilitated accountability; (2) MBCT-D-TiF provided mental health benefits, including tools to lessen the negative impact of depression and anxiety, increase connections to the world, and enhance positive experiences; (3) participants' home practices were reinvigorated during the weekly MBCT-D-TiF sessions, but fell short of their goals thereafter. Conclusion: MBCT-D-TiF was well attended and rated very or extremely helpful by most participants, supporting its feasibility and acceptability. Qualitative data showed that additional steps to help participants sustain home practice are needed, offering a target for refinement and further testing.

Indexed as

behavioral maintenance programdepressive disordermental healthmind-body therapiesmindfulnessmindfulness-based cognitive therapy (MBCT)

Identifiers

PMID41383293
PMCPMC12690042

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.