ArticleFrontiers in neurology2025
Analysis of 90-day risk factors for poor prognosis in patients with postoperative CT with hyperdense signs after thrombectomy for acute ischemic stroke.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the risk factors associated with poor 90-day prognosis in patients exhibiting hyperdense signs on the initial CT scan after mechanical thrombectomy for acute ischemic stroke. Methods: We conducted a retrospective analysis of 96 patients with acute ischemic stroke who underwent mechanical thrombectomy at The Affiliated Yongchuan Hospital of Chongqing Medical University. The patients were divided into a training set ( Results: Logistic regression analysis identified the following risk factors for poor 90-day prognosis: D-dimer level, admission diastolic blood pressure, preoperative NIHSS score, vascular occlusion site, as well as the volume of hyperdense areas and the total volume of both hyperdense and hypodense areas on the first postoperative CT scan. Two models were developed: one based solely on an imaging indicator (total volume) and another incorporating combined indicators (total volume, D-dimer, admission diastolic blood pressure, preoperative NIHSS score, and vascular occlusion site). The combined-indicator model demonstrated superior performance. In the training set, it achieved an AUC of 0.886 (95% CI: 0.801-0.971, Conclusion: Patients with hyperdense signs on the first postoperative CT scan exhibit distinct risk factors for poor 90-day prognosis. Combining imaging features with clinical indicators significantly improves the predictive value for 90-day outcome after mechanical thrombectomy.
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