Evidence map›Paper›PMID 41383167›Full record

ArticleJournal of global health2025

Estimating the economic burden of respiratory syncytial virus infection among children <2 years old seeking care in North-West Nigeria.

Farina Leonie Shaaban, Maria Ahuoiza Garba, An Nguyen, Clint Pecenka, Neele Rave, Louis J Bont

Abstract read
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Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farina Leonie ShaabanDepartment of Paediatrics, University Medical Centre Utrecht, Utrecht, the Netherlands.
Maria Ahuoiza GarbaDepartment of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
An NguyenCenter for Vaccine Innovation and Access, PATH, Ho Chi Minh City, Vietnam.
Clint PecenkaCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Neele RaveDepartment of Paediatrics, University Medical Centre Utrecht, Utrecht, the Netherlands.
Louis J BontDepartment of Paediatrics, University Medical Centre Utrecht, Utrecht, the Netherlands.

Funding

Gates Foundation INV-007610
6 · The paper itself

Abstract

Background: Respiratory syncytial virus (RSV) disease burden is highest in low- and middle-income countries; yet data for costs of RSV-related illness in these settings are scarce. We estimated RSV costs of illness to inform decision-making for RSV preventive strategies in Nigeria. Methods: This prospective study assessed the costs of care per episode of (severe) acute respiratory infection during one RSV season (April to November 2023). Children <2 years old, were recruited at tertiary inpatient and outpatient facilities in North-West Nigeria and grouped as non-severe (outpatient), severe (inpatient non-intensive care), and life-threatened (intensive care or fatality) cases. Direct medical, direct non-medical, and indirect cost data were collected using caregiver questionnaires at the index visit or day of admission and follow-up and gathered from hospital records at discharge. We summarised average costs in 2023 USD. Results: We included 792 children (mean age 8.7 months) with non-severe (n = 692), severe (n = 52), and life-threatening (n = 48) respiratory infections. Among these groups we confirmed RSV infection in 130 (19%), 19 (37%), and 14 (29%) children. The average societal costs were USD 13 (95% confidence interval (CI) = 11-14), USD 244 (95% CI = 198-290), and USD 179 (95% CI = 120-239) per episode of non-severe, severe, and life-threatening RSV infection, respectively. Costs associated with RSV did not increase stepwise with the severity categories due to small group sizes and fatalities with low costs included in the life-threatened group. For severe RSV, average household costs were over 200% of the national monthly minimum wage. Most households (89%) resorted to personal savings to cover costs. Conclusions: In young children in Nigeria, RSV presented a significant health and economic burden. This study can inform health economic evaluations of emerging RSV pharmaceutical interventions for Nigeria and may be adjusted for rural/urban contexts and level of care.

Indexed as

Cost of IllnessHealth Care CostsRespiratory Syncytial Virus InfectionsFemaleHumansInfantMaleNigeriaProspective Studies

Identifiers

PMID41383167
PMCPMC12699286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.