ArticleRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Prognostic factors of oral squamous cell carcinoma: a five-year retrospective study in Cluj-Napoca, Romania.
Article in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Novel Fibrosis-Integrated Nomogram for Predicting Survival in Oral Squamous Cell Carcinoma Patients with Oral Submucous Fibrosis: A Retrospective Cohort Study.Cancer management and research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveThe survival of patients with oral squamous cell carcinoma (OSCC) is influenced not only by tumor characteristics but also by treatment strategies, follow-up, and patient-related factors. This study aimed to determine the overall five-year survival rate in a Romanian cohort and evaluate the impact of key prognostic factors. PATIENTS, MATERIALS AND
methodsSeventy-two patients diagnosed with OSCC and treated surgically at the Department of Oral and Maxillofacial Surgery, Emergency County Clinical Hospital, Cluj-Napoca, Romania, between January 2016 and December 2019 were retrospectively analyzed. Prognostic factors included tumor stage, primary site, histological parameters, lymph node involvement, treatment modalities, and demographic variables.
resultsPatients were stratified into four groups: five-year survivors (n=26), disease-specific mortality (n=21), mortality from non-oncological causes (n=5), and lost to follow-up (n=20). Overall, 36.1% of patients achieved five-year recurrence-free survival, corresponding to 50% among those with complete follow-up. Survivors were more often diagnosed at early or intermediate stages, had fewer tongue tumors, better differentiation, clear surgical margins, and consistent adjuvant therapy. Notably, 27.8% of patients were lost to follow-up despite favorable pathological features, suggesting systemic gaps in long-term surveillance.
conclusionsThe five-year survival rate of 50% reflects both aggressive tumor biology and systemic barriers to care. Clinical stage remains the strongest prognostic factor, but tumor site and histological features, including perineural and lymphatic invasion, significantly influence outcomes even in early disease. Improved long-term survival requires earlier diagnosis, refined prognostic assessment, and multimodal therapy tailored to tumor behavior, alongside better patient follow-up strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.