Observational studyRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Assessment of the clinical and morphological characteristics of visceral melanoma metastases and primary extracutaneous melanomas.
Observational study in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
aimThis study aimed to assess the clinical and morphological characteristics of patients with visceral melanoma metastases and primary extracutaneous melanomas. PATIENTS, MATERIALS AND
methodsWe performed a retrospective study on patients with visceral melanoma metastases and primary extracutaneous melanomas, diagnosed in two pathology departments.
resultsWe identified 50 cases of visceral metastases and eight cases of primary extracutaneous melanomas. A percentage of 56% of the distant metastases involved the brain, 28% were localized in the digestive tract (stomach, small bowel, colon, liver, cystic duct), 16% involved the lung, spleen, adrenal gland, peritoneum, urinary bladder and bone. In 34% of the cases, the metastases were diagnosed prior to the primary melanoma. A percentage of 62.5% of primary extracutaneous melanomas were ocular melanomas, 25% were anal mucosa melanomas and one case (12.5%) involved the penile glans. Statistical analysis showed that distant melanoma metastases were more frequently diagnosed in the seventh decade (p<0.0001), and a higher percentage of patients lived in urban areas (p=0.001). The majority of the primary cutaneous melanomas associated with brain metastases were located on the trunk (p=0.0565). The brain metastases were more frequently diagnosed in males (64%; p=0.0604).
conclusionsThe brain is the most frequent organ involved by distant melanoma metastases, followed by the digestive tract. It is important to be aware of the least common metastatic locations such as cystic duct, urinary bladder, adrenal gland, spleen and peritoneum, in order to avoid misdiagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.