Evidence map›Paper›PMID 41382298›Full record

ArticleTrials2025

Cross-sectoral use of Patient-Reported Outcomes (C-PRO)-the effect on the cost per improvement in quality of life for patients with chronic degenerative shoulder conditions-a protocol for a randomised controlled trial.

Anne Marie Nyholm, Bente Appel Esbensen, Caroline Louise Westergaard, Jakob Kjellberg, Carsten Bogh Juhl, Bo Sanderhoff Olsen, Anders Odgaard

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06435494 (C-PRO - The Effect of Cross-sectorial Use of Patient-Reported Outcomes for Patients With Chronic Degenerative Shoulder Conditions), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06435494 naenrolling by invitationnot on this map

C-PRO - The Effect of Cross-sectorial Use of Patient-Reported Outcomes for Patients With Chronic Degenerative Shoulder Conditions

TypeinterventionalSponsorUniversity Hospital, Gentofte, CopenhagenRan2024 to 2030Enrolled1,000ConditionsShoulder Disease, Shoulder Impingement, Shoulder Osteoarthritis, Shoulder FrozenArmsSystematic use of patient reported outcome measures in clinical work with the patients
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne Marie NyholmThe Shoulder and Elbow Unit, Department of Orthopaedic Surgery, Copenhagen University Hospital-Herlev-Gentofte, Copenhagen, Denmark. rienyholm@gmail.com.ORCID http://orcid.org/0000-0001-9497-6853
Bente Appel EsbensenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Caroline Louise WestergaardVIVE-The Danish Centre for Social Science Research, Copenhagen, Denmark.
Jakob KjellbergVIVE-The Danish Centre for Social Science Research, Copenhagen, Denmark.
Carsten Bogh JuhlDepartment of Physiotherapy and Occupational Therapy, Copenhagen University Hospital-Herlev-Gentofte, Copenhagen, Denmark.
Bo Sanderhoff OlsenThe Shoulder and Elbow Unit, Department of Orthopaedic Surgery, Copenhagen University Hospital-Herlev-Gentofte, Copenhagen, Denmark.
Anders OdgaardDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Funding

Novo Nordisk Fonden NNF210C0067043
6 · The paper itself

Abstract

backgroundThis study aims to investigate the effect of the systematic use of patient-reported outcomes (PROs) across healthcare sectors on treatment outcomes and cost-effectiveness (measured as cost per improvement in quality of life) in people with chronic degenerative shoulder conditions.

methodsIn this randomised controlled trial with a 1-year inclusion period and 2-year follow-up, patients with a degenerative shoulder condition (glenohumeral impingement/pain of the acromioclavicular joint, glenohumeral osteoarthritis, rotator cuff degeneration or frozen shoulder) will be included. Every 2nd month, they will be asked to complete questionnaires about the shoulder function (Oxford Shoulder Score), quality of life (EQ-5D-5L) and a trial-specific questionnaire. Healthcare contacts at the general practitioner (GP), the orthopaedic department and the municipal physiotherapeutic centres will be registered prospectively during the follow-up period. In the intervention group, all collected data will be available to the patient and any treating party (GP, orthopaedic surgeons and physiotherapists). For the control group, trial data will be collected, but neither patient nor healthcare professionals will have access to these. After trial termination, follow-up data on use of healthcare services during the 2-year follow-up time will be collected from the Danish National Registries and the intervention and the control group will be compared with regard to use of healthcare services and satisfaction with the evaluation and treatment of their shoulder problem. DISCUSSION: Systematic use of PROs may be a tool to provide patients and clinicians with an insight into symptom development during treatment and to optimise both the treatment of the individual patient as well as a smarter use of the resources available in the healthcare system. The inclusion of patients begins on the 12th of August 2024.

trial registrationClinicalTrials.gov NCT06435494. Registration date 16th of May 2024.

Indexed as

Health Care CostsOsteoarthritisPatient Reported Outcome MeasuresQuality of LifeShoulder JointShoulder PainChronic DiseaseCost-Benefit AnalysisHumansMulticenter Studies as TopicRandomized Controlled Trials as TopicTreatment OutcomeAC joint arthrosisDegenerative rotator cuff diseaseDegenerative shoulder diseaseFrozen shoulderGlenohumeral arthrosisHealthcare economicsImpingementPatient-reported outcomeQuality of life

Identifiers

PMID41382298
PMCPMC12817683

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.