ArticleInternational journal of retina and vitreous2025
Optical coherence tomography findings in acute central retinal artery occlusion and their association with visual outcomes.
Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Spontaneous Head Turn in Central Retinal Artery Occlusion With Nasal Cilioretinal Artery Sparing: A Case Report.The American journal of case reports · 2026Article
- En face OCT in branch retinal artery occlusion: quantitative assessment of epiretinal macrophage-like cells and optical intensity ratio.BMC ophthalmology · 2026Article
- Retinal layer reflectivity and thickness as OCT biomarkers for diagnosis and imaging-based stratification relative to the 4.5-h window in acute central retinal artery occlusion.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
objectivesThis study aimed to summarize the optical coherence tomography (OCT) findings in central retinal artery occlusion (CRAO) and investigate their association with visual outcomes.
methodIn this retrospective study, 63 cases (63 eyes) of CRAO were included. Clinical data, including age, gender, time of symptom onset, visual acuity (VA) and OCT images were collected and analysed. The morphology and reflectivity of different retinal layers on OCT images were assessed, and retinal thickness was measured using the built-in software of OCT system. The optical intensity of the retina was quantified using ImageJ software.
resultsThe OCT findings in the 63 CRAO eyes were characterized by hyperreflectivity in the inner retinal layers (62 eyes, 98.4%) and retinal thickening (61 eyes, 96.8%), along with prominent middle limiting membrane (p-MLM) (42 eyes, 66.7%), hyporeflectivity of para-foveal outer retina (41 eyes, 65.1%), indistinct inner retinal layers (29 eyes, 46.0%), and foveal deformation (26 eyes, 41.3%). The inner and full retinal thickness in CRAO eyes was moderately positively correlated with the logarithm of the minimum angle of resolution (logMAR) VA at initial presentation and the last follow-up. Additionally, the optical intensity of the outer nuclear layer (ONL) and ellipsoid zone (EZ)-RPE complex was moderately negatively correlated with logMAR VA at presentation and the last follow-up. The ratio of inner retinal optical intensity to EZ/RPE optical intensity was moderately positively correlated with logMAR VA.
conclusionOCT may assist in assessing visual outcomes in patients with CRAO. Retinal thickening and inner retinal hyperreflectivity are key OCT findings in CRAO, and these changes could provide valuable prognostic information.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.