Evidence map›Paper›PMID 41382096›Full record

ArticleBMC public health2025

Implementing digital interventions for co-occurring mental health and alcohol and other drug use problems in health and community settings: a study protocol for the eCliPSE cluster randomised controlled trial.

Milena Heinsch, Hannah Wells, Campbell Tickner, Dara L Sampson, Jane Rich, Jamie Carlson, Maree Teesson, Cathrine Mihalopoulos, Matthew Sunderland, Helen Christensen and 12 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Milena HeinschSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Hannah WellsSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Campbell TicknerSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Dara L SampsonSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Jane RichSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Jamie CarlsonNewcastle Business School, The University of Newcastle, Callaghan, NSW, Australia.
Maree TeessonThe Matilda Centre for Research in Mental Health and Substance Use, University of Sydney, Camperdown, NSW, Australia.
Cathrine MihalopoulosSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Matthew SunderlandThe Matilda Centre for Research in Mental Health and Substance Use, University of Sydney, Camperdown, NSW, Australia.
Helen ChristensenFaculty of Medicine & Health, University of New South Wales, Randwick, NSW, Australia.
Paul HaberSpecialty of Addiction Medicine, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Kirsten MorleySpecialty of Addiction Medicine, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Andrew BaillieSydney School of Health Sciences, Faculty of Medicine & Health, University of Sydney, Camperdown, NSW, Australia.
Jessica WyllieNewcastle Business School, The University of Newcastle, Callaghan, NSW, Australia.
Timothy ShawFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Mary Lou ChattertonSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Clare CorlissSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Gurmeher GulhatiSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Danielle SimmonetteSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Sally HuntSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Louise Thornton *School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia. louise.thornton@sydney.edu.au.
Frances Kay *School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMental health and alcohol and other drug use problems consistently dominate the top causes of disease burden in Australians. eHealth stands to be a key tool in addressing these issues but is not routinely well-integrated into service provision models. This study will evaluate the uptake of the digital ecosystem and website, eCliPSE [electronic Clinical Pathways to Service Excellence], developed to improve the symptoms of mental health and alcohol and other drug use problems in people experiencing comorbidity. It will compare two different implementation strategies designed to engage consumers and health services with the eCliPSE website.

methodsA cluster randomised controlled trial involving participants from 30 Australian public mental health and alcohol and other drug use services and 8 private psychology services will be conducted across the 15 local health districts in NSW. Each district will be randomised to receive one of two interventions: a Direct-to-Consumer [DtC] Marketing Strategy, or the DtC strategy in addition to an Integrated Translation and Engagement Model [ITEM] of implementation developed by the research team. The effectiveness of each strategy in encouraging uptake of eCliPSE (number of registrations) will be evaluated and compared. Data will be collected using a combination of the eCliPSE website and social media analytics, quantitative surveys, ethnographic observation, document review and qualitative interviews. An economic evaluation will also estimate the cost-effectiveness of DtC + ITEM and budget impact of the strategies, if implemented across Australia. DISCUSSION: It is expected that the DtC marketing strategy will result in significant uptake of eCliPSE, that districts receiving DtC + ITEM will demonstrate significantly greater uptake of eCliPSE than those receiving DtC only, and that the combined strategy will be cost-effective compared to DtC alone. Findings from this study will inform future integration and upscaling of digital health tools into traditional service settings for mental health and alcohol and other drug use across Australia.

trial registrationThis trial is registered with the Australian New Zealand Clinical Trials Registry as: The eCliPSE Project: A 3-level cluster randomised controlled trial implementing evidence-based eHealth interventions for comorbid mental health and alcohol/other drug use problems into health and community settings. Registration number: ACTRN12622000333718. Registration date: 23rd of February 2022.

Indexed as

Mental DisordersSubstance-Related DisordersAustraliaComorbidityDigital HealthHumansNew South WalesRandomized Controlled Trials as TopicTelemedicineAlcohol and other drug useComorbidityDigital healthEHealth implementationInterventionMental health

Identifiers

PMID41382096
PMCPMC12882599

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.