Evidence map›Paper›PMID 41381928›Full record

ArticleAnnals of surgical oncology2026

Breast Cancer Presentation and Treatment Patterns in Sexual and Gender Minorities.

Gabi Barmettler, Saskia Leonard, Andreas Giannakou, Ko Un Park, Claire E Smith, Elizabeth A Mittendorf, Tari A King, Olga Kantor

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabi BarmettlerDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Saskia LeonardDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Andreas GiannakouDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Ko Un ParkDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Claire E SmithBreast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA.
Elizabeth A MittendorfDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Tari A KingDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Olga KantorDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA. olga.kantor@northwestern.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to examine differences in breast cancer presentation, management, and outcomes between sexual and gender minority (SGM) patients and cisgender heterosexual women (CHW).

methodsA prospective institutional database was reviewed to identify patients who had surgical management for clinical stage 0-III breast cancer from 2016 to 2023. SGM patients were identified as those who had self-documented in the medical record as lesbian, gay, bisexual, transgender, nonbinary, queer, intersex, asexual, nonbinary, or pansexual. Descriptive statistics were used to compare characteristics of SGM patients and CHW.

resultsAmong 5346 patients, 5204 (97.3%) identified as CHW and 142 (2.7%) identified as SGM. There were no differences in presenting symptoms, stage, grade, or subtype between groups. SGM patients were more likely to be diagnosed under the age of 50 (38.7% SGM vs. 30.0% CHW, p=0.03) and to undergo mastectomy (42.6% SGM vs. 34.3% CHW, p=0.04). Among those undergoing mastectomy, SGM patients were less likely to have reconstruction (53.3% vs. 73.2%, p<0.01). Rates of adjuvant radiation and systemic therapy were similar. At a median follow-up of 30 months, there were no differences in the rate of invasive disease recurrence (0.8% SGM vs. 1.3% CHW, p=0.66).

conclusionsSGM and CHW patients with breast cancer treated in a tertiary cancer center had similar breast cancer presentation, treatment, and outcomes. SGM patients were less likely to undergo breast conservation and reconstruction after mastectomy, suggesting that SGM identity may play a role in preference for type of local therapy.

Indexed as

Breast NeoplasmsMastectomySexual and Gender MinoritiesAdultAgedFemaleFollow-Up StudiesHumansMammaplastyMiddle AgedPrognosisProspective StudiesBreast cancerCisgenderGender minoritiesLGBTQIASexual minorities

Identifiers

PMID41381928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.