Evidence map›Paper›PMID 41381804›Full record

SynthesisInternational urology and nephrology2026

Penile skin graft versus buccal mucosal graft for anterior urethral strictures in adult urethroplasty- a systematic review and meta-analysis.

Syed Moiz Abbas, Muhammad Farhan, Areeba Khan, Safa Mazhar, Rimsha Imran, Hiba Zafar, Suheera Afzoon, F N U Areeba

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Syed Moiz AbbasDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan. moizabbas61@gmail.com.ORCID http://orcid.org/0009-0009-6712-7421
Muhammad FarhanDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0009-0007-0632-3846
Areeba KhanDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0009-0003-4675-2822
Safa MazharDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0009-0002-0152-6875
Rimsha ImranDepartment of Radiology, Fatima Memorial Hospital, Lahore, Pakistan.ORCID http://orcid.org/0009-0002-4222-2317
Hiba ZafarDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0009-0008-0826-519X
Suheera AfzoonDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0009-0003-4617-2043
F N U AreebaDepartment of Medicine, Dow University of Health Sciences, Karachi, Pakistan.ORCID http://orcid.org/0009-0008-8632-1222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrethral strictures are a prevalent condition commonly involving the anterior urethra for which urethroplasty remains the gold standard treatment. BMG and PSG are most widely used for the repair, yet their comparative efficacy remains debated.

methodsA systematic literature review was performed consistent with PRISMA guidelines. Literature searches were performed on PubMed, Embase and the Cochrane Library. Studies were considered eligible if they were comparing BMG and PSG for urethroplasty in adult patients with anterior urethral strictures. Statistical analysis was carried out on RevMan 5.4, employing a random-effects model driving pooled odds ratios (OR) and mean differences (MD) with 95% confidence intervals (CI). Subgroup analysis and sensitivity analysis was performed.

results11 included studies (n = 1018) showed that success rate was significantly higher in PSG compared to BMG (OR: 0.52, P = 0.0004). Analysis of secondary outcomes demonstrated a marginally and statistically significant advantage of PSG in improving IPSS at 6 months (MD: 0.53, P = 0.05) and 18 months (MD: 0.91, P = 0.002) respectively, with a borderline enhancement in erectile function (IIEF-ED) at 18 months (MD 1.27, P = 0.05). No statistically significant differences were observed for other outcomes.

conclusionIn this pooled analysis, PSG was associated with a higher success rate, though this finding must be interpreted with caution due to the inconsistent definitions of success and follow-up durations, variability among surgery methods and graft types. Moreover this meta-analysis demonstrate that PSG in comparison to BMG has modest advantages in urinary and erectile function with comparable outcomes across most secondary parameters, supporting PSG as a viable alternative to BMG.

Indexed as

Mouth MucosaPenisSkin TransplantationUrethraUrethral StrictureAdultHumansMaleUrologic Surgical Procedures, MaleAnterior urethral stricturesBMGBuccal Mucosa GraftPenile Skin GraftPSGUrethral strictureUrethroplasty

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.