Evidence map›Paper›PMID 41381768›Full record

ArticleActa neurochirurgica2025

Incidence rates of paediatric traumatic brain injury in Denmark - the development over three decades: a nationwide, population-based registry study.

Yasemin Ronahi Kücük, Sarah Hornshøj Pedersen, Mikael Andersson, Christian Gunge Riberholt, Christina Kruuse, Marin Strøm, Tina Nørgaard Munch

Erratum issuedAbstract read
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yasemin Ronahi KücükDepartment of Brain and Spinal Cord Injury, Copenhagen Neuro Injury and Rehabilitation Research Centre (CNIRC), Rigshospitalet Neurocentret, Copenhagen, Denmark.ORCID http://orcid.org/0009-0001-0249-6463
Sarah Hornshøj PedersenDepartment of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen S, Denmark. sarah.skovlunde.hornshoej.pedersen.01@regionh.dk.ORCID http://orcid.org/0000-0002-3436-6081
Mikael AnderssonDepartment of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen S, Denmark.ORCID http://orcid.org/0000-0002-0114-2057
Christian Gunge RiberholtDepartment of Brain and Spinal Cord Injury, Copenhagen Neuro Injury and Rehabilitation Research Centre (CNIRC), Rigshospitalet Neurocentret, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-6170-1869
Christina KruuseDepartment of Brain and Spinal Cord Injury, Copenhagen Neuro Injury and Rehabilitation Research Centre (CNIRC), Rigshospitalet Neurocentret, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4210-0523
Marin StrømFaculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands.ORCID http://orcid.org/0000-0003-1926-6610
Tina Nørgaard MunchDepartment of Neurosurgery, Rigshospitalet, Lehmanns Vej 8, 2100, Copenhagen E, Denmark.ORCID http://orcid.org/0000-0001-5938-000X

Funding

The Council of the Danish Victims Fund 22-610-00181The Health Foundation 20-B-0307The Research Fund of Rigshospitalet, Copenhagen University Hospital E-22218-07
6 · The paper itself

Abstract

backgroundPaediatric traumatic brain injury (TBI) is a major global health concern and a leading cause of mortality and disability in children. Despite extensive research, knowledge on incidence based on national health registers is scarce. This study aimed to estimate incidence rates (IR) of TBI across all severity levels over three decades in Danish children.

methodsThrough a nationwide, population-based registry study we identified all children aged 0 to < 15 years born in Denmark between 1977 and 2018. Children were included at birth or immigration and followed until their 15th birthday, death, emigration, or December 31st, 2018. Incident TBIs were classified as minimal, mild, moderate, or severe.

resultsAmong 3,235,391 children, 127,158 had a TBI before age 15 (56.8% male). The overall IR declined over the study period, with a significant reduction from 498.2 (95% CI 491.6-504.9) per 100,000 person-years (pyrs) in 1985-1989 to 336.2 (95% CI 330.4-342.0) in 2015-2018,the lowest rate observed. IRs for mild, moderate, and severe TBI declined to 50.8, 3.5, and 3.5 per 100,000 pyrs, respectively. In contrast, IR of minimal TBI continued to increase over time. Males consistently exhibited higher IRs, although both sexes showed a steady decline after 1999.

conclusionPaediatric TBI incidence in Denmark has declined over three decades, likely reflecting national prevention strategies e.g. traffic regulations. Nevertheless, incidence remains high, particularly among children aged 0 to < 3 years and males. These findings provide essential data to inform public health initiatives, while highlighting the need for injury prevention.

Indexed as

Brain Injuries, TraumaticRegistriesAdolescentChildChild, PreschoolDenmarkFemaleHumansIncidenceInfantInfant, NewbornMaleChildrenEpidemiologyIncidence ratePaediatric TBIPaediatric traumatic brain injuryPopulation-based study

Identifiers

PMID41381768
PMCPMC12700919

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.