Evidence map›Paper›PMID 41381732›Full record

ReviewThe EMBO journal2026

The Golgi apparatus: adaptations to neuronal shape and functions.

Aygul Subkhangulova, Marina Mikhaylova

Abstract readReview
In one paragraph

Review in The EMBO journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aygul Subkhangulova *German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. aygul.subkhangulova@dzne.de.ORCID 0000-0001-8843-0678
Marina Mikhaylova *AG Optobiology, Institute of Biology, Humboldt-Universität zu Berlin, Berlin, Germany. marina.mikhaylova@hu-berlin.de.ORCID 0000-0001-7646-1346

Funding

Deutsche Forschungsgemeinschaft (DFG) EXC-2049-390688087Deutsche Forschungsgemeinschaft (DFG) FOR5228 RP4Deutsche Forschungsgemeinschaft (DFG) Walter Benjamin Programme
6 · The paper itself

Abstract

The Golgi apparatus is the central hub of secretory and endosomal pathways in a eukaryotic cell. Despite having a conserved basic organization, the Golgi varies greatly in structure and operation mode between different cell types, ranging from dispersed cisternae in the budding yeast to the ribbon of cisternae stacks in most mammalian cells. Cell shape and secretory demands dictate structural and functional properties of the Golgi. Neurons are a particularly interesting type of secretory cells that have a highly polarized architecture and a large and diverse secretome. The neuronal Golgi complex evolved into an elaborate set of compartmentalized organelles that process and sort diverse neuronal cargos, including synaptic proteins, neuropeptides, and neurotrophic factors. In this review, we describe the structural adaptations of the Golgi to neuronal architecture and discuss the principles of neuronal cargo sorting. We also highlight structural rearrangements of the neuronal Golgi in neurodegenerative diseases and discuss the role of mutations in Golgi-related proteins in neurodevelopment.

Indexed as

Golgi ApparatusNeuronsAnimalsHumansNeurodegenerative DiseasesGolgi ComplexGolgi SatellitesNeuronal SecretionTrafficking

Identifiers

PMID41381732
PMCPMC12811389

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.