Evidence map›Paper›PMID 41381625›Full record

ArticleScientific reports2025

Prevalence and impact of long COVID on health-related quality of life in previously hospitalized COVID-19 patients: a 2-year follow-up study.

Patharapan Lersritwimanmaen, Achiraya Thonghem, Walaiporn Wongsrisakunkaew, Chayanis Kositamongkol, Pochamana Phisalprapa

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PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patharapan LersritwimanmaenDivision of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. patharapan.ler@mahidol.ac.th.
Achiraya ThonghemDivision of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Walaiporn WongsrisakunkaewDivision of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Chayanis KositamongkolDivision of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Pochamana PhisalprapaDivision of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long COVID is a major health concern, yet evidence from Southeast Asia remains limited. We evaluated the prevalence, predictors, and health-related quality of life (HRQoL) impact of long COVID among hospitalized adults in Thailand over two years. This single-center, ambidirectional cohort combined retrospective chart review with prospective follow-up. The cohort comprised 295 adults hospitalized for symptomatic COVID-19 between August and November 2021. Interviews occurred at three months, one year, and two years post-infection. Long-COVID prevalence was 49.8% at three months; among these, 64.4% reported persistent symptoms at one year, and 22% of the one-year symptomatic group had symptoms at two years. Common symptoms included breathlessness, fatigue, and memory disturbance. Logistic regression identified severe-critical acute illness as a risk factor (adjusted odds ratio [aOR] 2.06, 95% CI 1.23-3.46), while full vaccination was protective (aOR 0.48, 95% CI 0.25-0.90). Long COVID was associated with lower HRQoL across all EQ-5D-5L domains. Long COVID was frequent among hospitalized Thai patients, with symptoms persisting in a substantial proportion up to two years. Severity of acute COVID-19 and vaccination status predicted long COVID. Long COVID was linked to reduced HRQoL, underscoring the need for follow-up and further confirmation in larger, multicenter studies.

Indexed as

COVID-19Quality of LifeAdultAgedFatigueFemaleFollow-Up StudiesHospitalizationHumansMaleMiddle AgedPost-Acute COVID-19 SyndromePrevalenceProspective StudiesRetrospective StudiesRisk FactorsCOVID-19Health-related quality of lifeLong COVIDPost-acute sequelae of SARS-CoV-2 infection (PASC)PrevalenceRisk factors

Identifiers

PMID41381625
PMCPMC12804989

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.