Evidence map›Paper›PMID 41381587›Full record

ArticleNature communications2025

Engineering microbial consortia for mixed plastic upcycling.

Jinjin Diao, Yuxin Tian, Sunkyu Park, Seong-Min Cho, Tae Seok Moon

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Elucidating biodegradation of dimethyl terephthalate by twoMetabolic engineering communications · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinjin Diao *Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Yuxin Tian *Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Sunkyu ParkDepartment of Forest Biomaterials, North Carolina State University, Raleigh, NC, USA.ORCID http://orcid.org/0000-0002-9332-9061
Seong-Min ChoDepartment of Forest Biomaterials, North Carolina State University, Raleigh, NC, USA. scho26@ncsu.edu.ORCID http://orcid.org/0000-0001-7497-8747
Tae Seok MoonSynthetic Biology Group, J. Craig Venter Institute, La Jolla, CA, USA. tsmoon7@gmail.com.ORCID http://orcid.org/0000-0001-8373-9051

Funding

DOE | SC | Biological and Environmental Research (BER) DE-SC0022003National Science Foundation (NSF) EF-2222403National Science Foundation (NSF) OISE-2435184
6 · The paper itself

Abstract

Recent studies in developing processes using 'single' plastic waste for microbial conversion have demonstrated great promise in advancing a circular economy. However, chemical complexity and compositional variability of post-consumer 'mixed' plastic waste pose huge challenges to using it as a feedstock for biomanufacturing. Here, we present a process leveraging a synthetic microbial consortium, comprising Rhodococcus jostii strain PET and Acinetobacter baylyi ADP1, enabled by engineering the division of labor. The robust consortium synergistically and stably consumes diverse mixtures of oxygenated compounds, derived from the depolymerization of post-consumer, mixed plastic waste, regardless of the fluctuating plastic waste compositions. We evaluate the upcycling potential of the stable consortium by applying rational metabolic engineering to both specialists, enabling the funneling of these oxygenates into lycopene and lipids. This work highlights the potential of stable microbial consortia to valorize untapped, mixed plastic waste for sustainable biomanufacturing, offering a promising solution to global plastic pollution.

Indexed as

AcinetobacterMetabolic EngineeringMicrobial ConsortiaPlasticsRhodococcusLycopeneLycopenePlastics

Identifiers

PMID41381587
PMCPMC12816627

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.