ArticleNature communications2025
Hippocampal-prefrontal orchestration supports higher-order learning for creative ideation.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
We learn not just to remember, but also to create. Yet, the neurocognitive foundations by which higher-order learning fosters subsequent creation remain elusive. After verifying the facilitating effects of creative exemplar-learning on subsequent creation, this study identified hippocampal and prefrontal encoding patterns during exemplar-learning that predict higher (HSC) or lower (LSC) subsequent creation. The HSC condition was characterized by reduced hippocampal representational dimensionality and increased hippocampal-ventrolateral prefrontal cortex (vlPFC) connectivity-effects independent of exemplar memory and consistent across textual and pictorial exemplar materials. Cross-phase analyses revealed that low-dimensional hippocampal and full-dimensional vlPFC representations transferred more effectively from learning to creating in HSC trials. Moreover, cross-phase decoding function in the vlPFC for discriminating HSC from LSC trials relied on low-dimensional hippocampal representations during learning. Together, these findings show that hippocampal-vlPFC orchestration abstracts and transfers exemplar information to support creativity, revealing a neurocognitive mechanism of higher-order learning distinct from memory acquisition.
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