Evidence map›Paper›PMID 41381223›Full record

ArticleThe European respiratory journal2026

Nasal epithelium and blood transcriptomic signatures associations with smoking and exacerbations.

Vickram Tejwani, Arunangshu Sarkar, Claire J Guo, Satria Sajuthi, Peter Castaldi, Laura E Crotty Alexander, Igor Z Barjaktarevic, Alejandro P Comellas, Jennifer Dawson, Dawn L DeMeo and 8 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The European respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Vickram TejwaniDepartment of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA Tejwanv@ccf.org.ORCID https://orcid.org/0000-0003-2100-6148
Arunangshu SarkarUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-0648-4750
Claire J GuoDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Satria SajuthiCenter for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Peter CastaldiChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Laura E Crotty AlexanderMedicine Service, Pulmonary and Critical Care Section, Veterans Affairs San Diego Healthcare System, La Jolla, CA, USA.
Igor Z BarjaktarevicDivision of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Alejandro P ComellasDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa, Iowa City, IA, USA.ORCID https://orcid.org/0000-0003-1521-7520
Jennifer DawsonGenomic Sciences and Systems Biology, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
Dawn L DeMeoChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Craig P HershChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Lisa RuvunaDepartment of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA.
Sunita SharmaDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Edwin K SilvermanChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Katherine A PratteDepartment of Biostatistics, National Jewish Health, Denver, CO, USA.
Max SeiboldCenter for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.ORCID https://orcid.org/0000-0002-8685-4263
Katerina KechrisUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Russell P BowlerDepartment of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0003-4651-363X

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Leukotriene B4 and IL-8 in alpha-1 heterozygotes (PI*MZ genotype)K23HL173570 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI Vickram Tejwani · 2024 to 2026
$512k
NHLBI NIH HHS K23 HL173570NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41381223
PMCPMC13020525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.