Evidence map›Paper›PMID 41380087›Full record

ArticleACS nano2025

Multivalent Interactions between Chaperone and Ribosome-Nascent Chain Complex Revealed by High-Speed AFM and MD Simulations.

Eider Nuñez, Prithwidip Saha, Markel G Ibarluzea, Arantza Muguruza-Montero, Sara M-Alicante, Rafael Ramis, Aritz Leonardo, Aitor Bergara, Alvaro Villarroel, Felix Rico

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In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eider NuñezAix-Marseille University, INSERM, DyNaMo, Turing Centre For Living Systems, Marseille 13009, France.ORCID 0000-0001-8075-9815
Prithwidip SahaAix-Marseille University, INSERM, DyNaMo, Turing Centre For Living Systems, Marseille 13009, France.ORCID 0000-0003-2600-0415
Markel G IbarluzeaDonostia International Physics Center, Donostia 20018, Spain.
Arantza Muguruza-MonteroBiofisika Institute, CSIC-UPV/EHU, Leioa 48940, Spain.
Sara M-AlicanteBiofisika Institute, CSIC-UPV/EHU, Leioa 48940, Spain.
Rafael RamisDonostia International Physics Center, Donostia 20018, Spain.
Aritz LeonardoDonostia International Physics Center, Donostia 20018, Spain.ORCID 0000-0002-5942-2270
Aitor BergaraDonostia International Physics Center, Donostia 20018, Spain.ORCID 0000-0003-2707-1856
Alvaro VillarroelBiofisika Institute, CSIC-UPV/EHU, Leioa 48940, Spain.
Felix RicoAix-Marseille University, INSERM, DyNaMo, Turing Centre For Living Systems, Marseille 13009, France.ORCID 0000-0002-7757-8340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trigger Factor (TF) is a primary ATP-independent molecular chaperone in bacteria that engages nascent polypeptide chains emerging from the ribosomal exit tunnel to assist their folding. However, the real-time behavior of TF during active translation under near-physiological conditions remains elusive. Here, we employ high-speed atomic force microscopy (HS-AFM) imaging to visualize TF dynamics on intact

Indexed as

Escherichia coli ProteinsMicroscopy, Atomic ForceMolecular ChaperonesMolecular Dynamics SimulationPeptidylprolyl IsomeraseRibosomesEscherichia coliProtein ConformationRibosomal ProteinsEscherichia coli ProteinsMolecular ChaperonesPeptidylprolyl IsomeraseRibosomal Proteinstrigger factor, E coliatomic force microscopy imagingmolecular dynamics simulationsprotein foldingribosometrigger factor (chaperone)

Identifiers

PMID41380087
PMCPMC12752688

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.