Evidence map›Paper›PMID 41379939›Full record

ArticleScience (New York, N.Y.)2026

Spatial and morphological organization of mitochondria in neurons across a connectome.

Garrett Sager, Paul Pfeiffer, Heng Wu, Fabian Pallasdies, Robert Gowers, Snusha Ravikumar, Elizabeth Wu, Daniel Colón-Ramos, Susanne Schreiber, Damon A Clark

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mitochondrial molecular diversity in the brain.Current opinion in neurobiology · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Garrett SagerDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.ORCID 0000-0002-8002-8577
Paul PfeifferInstitute for Theoretical Biology, Humboldt University, Berlin, Germany.ORCID 0000-0001-5324-5886
Heng WuDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.
Fabian PallasdiesInstitute for Theoretical Biology, Humboldt University, Berlin, Germany.ORCID 0000-0001-5359-4699
Robert GowersInstitute for Theoretical Biology, Humboldt University, Berlin, Germany.ORCID 0000-0002-9673-9111
Snusha RavikumarDepartment of Neuroscience, Yale University, New Haven, CT, USA.ORCID 0000-0001-6215-9146
Elizabeth WuDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.
Daniel Colón-RamosDepartment of Neuroscience, Yale University, New Haven, CT, USA.ORCID 0000-0003-0223-7717
Susanne SchreiberInstitute for Theoretical Biology, Humboldt University, Berlin, Germany.ORCID 0000-0003-3913-5650
Damon A ClarkDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.ORCID 0000-0001-8487-700X

Funding

Examination of the cell biology of the synapse and behaviorR35NS132156 · NINDS · YALE UNIVERSITY · PI DANIEL A COLON-RAMOS · 2023 to 2026
$4.6M
Integrating visual counterevidence to detect self-motion in a small visual circuitR01EY026555 · NEI · YALE UNIVERSITY · PI CLARK, DAMON ALISTAIR · 2016 to 2025
$4.0M
NEI NIH HHS R01 EY026555NINDS NIH HHS R35 NS132156
6 · The paper itself

Abstract

Neuronal function depends on mitochondria, but little is known about their organization across neurons. Using an electron microscopy

Indexed as

ConnectomeMitochondriaNeuronsAnimalsDrosophila melanogasterMiceMicroscopy, ElectronSynapsesVisual Cortex

Identifiers

PMID41379939
PMCPMC12906887

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.