Evidence map›Paper›PMID 41379698›Full record

ArticleEmerging infectious diseases2025

Extensively Drug-Resistant Tuberculosis with Conflicting Resistance Testing Results, Lesotho.

Kwonjune J Seung, Meseret Asfaw, Mikanda Kunda, Llang Bridget Maama-Maime, Joalane Makaka, Mabatloung Mofolo, Stephane Mpinda, Melino Ndayizigiye, Shaheed Vally Omar, Prithiv Prasad and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kwonjune J Seung
Meseret Asfaw
Mikanda Kunda
Llang Bridget Maama-Maime
Joalane Makaka
Mabatloung Mofolo
Stephane Mpinda
Melino Ndayizigiye
Shaheed Vally Omar
Prithiv Prasad
Praharshinie Rupasinghe
Chase Yarbrough
Lawrence Oyewusi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient with extensively drug-resistant tuberculosis in Lesotho recovered successfully after failed treatment with bedaquiline, delamanid, linezolid, and clofazimine. Whole-genome sequencing and broth microdilution testing results were not in agreement, illustrating the urgent need for studies that correlate phenotypic and genotypic resistance testing with clinical response.

Indexed as

Antitubercular AgentsExtensively Drug-Resistant TuberculosisMycobacterium tuberculosisAdultDrug Resistance, Multiple, BacterialHumansLesothoMaleMicrobial Sensitivity TestsWhole Genome SequencingAntitubercular Agentsantimicrobial resistancebacteriaextensively drug-resistant tuberculosisgenotypic resistance testingLesothophenotypic resistance testingtuberculosistuberculosis and other mycobacteria

Identifiers

PMID41379698
PMCPMC12704540

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.