ArticleCell reports2025
Post-biting behavioral reprogramming underlies reproductive efficiency in Aedes aegypti mosquitoes.
Article in Cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Behavioral determinants of disease transmission by mosquitoes.Current opinion in insect science · 2026Review
- Mosquito heat and humidity detection in host seeking and oviposition behavior.Current opinion in neurobiology · 2026Review
- Advances in mosquito olfaction: Genetic, genomic, and behavioral approaches in Aedes aegypti.Current opinion in neurobiology · 2026Review
- Bridging laboratory and field research: Method adjustments to blood feed field-derived Aedes aegypti.PLoS neglected tropical diseases · 2026Article
- Behavioral heterogeneity in host seeking and post-feeding suppression among disease vector mosquitoes.Communications biology · 2026Article
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Abstract
The global spread and increasing populations of disease vector mosquitoes expose hundreds of millions of people to mosquito-borne illnesses each year. Female Aedes aegypti mosquitoes, global vectors of dengue and Zika, bite humans to obtain blood nutrients that support egg development. We report that, after a blood meal, female mosquitoes transition from a period of inactivity into active searching for egg-laying sites. Females with mature eggs show increased locomotor activity and a shift in circadian behavioral timing, leading to nocturnal humidity seeking and egg laying in an otherwise diurnal species. We show that the circadian clock gene cycle is critical for regulating this transition; its absence disrupts the timing of oviposition-related behaviors, causing reduced reproductive capacity when active site search is required. These findings suggest that, during egg development, circadian-clock-dependent behavioral reprogramming triggers nocturnal hyperactivity and oviposition site search, an essential process for mosquito reproduction and population viability.
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