Evidence map›Paper›PMID 41379541›Full record

ArticleScience progress

Association between visceral adiposity index and chronic obstructive pulmonary disease: A cross-sectional analysis.

Shaofeng Zhang, Yidan Lin, Zekui Fang, Xiping Wu, Jia Jiang, Yaling Zeng, Jiayi Liu, Jia Li, Kai Wang, Xinyu Song and 1 more

Abstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shaofeng ZhangDepartment of Respiratory and Critical Care Medicine, The first College of Clinical Medicine Science, China Three Gorges University, Yichang Central People's Hospital, Yichang, Hubei, China.ORCID 0000-0002-1981-8588
Yidan LinDepartment of Health Management, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Zekui FangPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.
Xiping WuPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.ORCID 0000-0003-1822-1664
Jia JiangPulmonary and Critical Care Medicine, The Eighth Affiliated Hospital of Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, Guangdong, China.
Yaling ZengPulmonary and Critical Care Medicine, The Eighth Affiliated Hospital of Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, Guangdong, China.
Jiayi LiuPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.ORCID 0009-0009-5984-9205
Jia LiPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.
Kai WangPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.ORCID 0000-0002-3980-7659
Xinyu SongDepartment of Respiratory and Critical Care Medicine, The first College of Clinical Medicine Science, China Three Gorges University, Yichang Central People's Hospital, Yichang, Hubei, China.
Qiang XiaoPulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China.ORCID 0000-0002-8643-4429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundPrevious studies suggest that obesity may exacerbate clinical manifestations of chronic obstructive pulmonary disease (COPD). Early detection of COPD could improve therapeutic outcomes. This study investigates the relationship between a novel metabolic biomarker, the Visceral Adiposity Index (VAI), and COPD risk. We hypothesized that higher VAI levels would be independently associated with an increased prevalence of COPD.MethodsThis study is a cross-sectional analysis of data from the National Health and Nutrition Examination Survey (NHANES) spanning the periods 1999-2018 and 2021-2023. Multivariable logistic regression was employed to assess the association between VAI and COPD, supplemented by subgroup stratification, smoothed curve fitting, and threshold effect analyses.ResultsAmong 16,167 participants, 1397 were diagnosed with COPD. Multivariable logistic regression revealed a positive correlation between VAI levels and COPD prevalence, independent of confounding factors. Subgroup analyses indicated stronger associations in hypertensive patients and females. Smoothed curve fitting identified a threshold effect for VAI, with an inflection point at 2.55 (P = 0.002).ConclusionThe findings of this study indicate a significant positive correlation between VAI levels and the prevalence of COPD. Maybe incorporating visceral adipose function assessment into the initial risk stratification system for high-risk populations with COPD holds certain clinical value.

Indexed as

AdiposityIntra-Abdominal FatObesity, AbdominalPulmonary Disease, Chronic ObstructiveAdultAgedBiomarkersCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsBiomarkersChronic obstructive pulmonary diseasecross-sectional studymetabolic syndromethe National Health and Nutrition Examination Surveyvisceral adiposity index

Identifiers

PMID41379541
PMCPMC12698969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.