Evidence map›Paper›PMID 41379086›Full record

SynthesisSpine2026

The Role of Electrophysiological Workup in Lumbar Spinal Canal Stenosis (LSCS): A Systematic Review.

Guichande Duarte, Markus Hupp, José Spirig, Mazda Farshad, Martin Schubert, Armin Curt, Patrick Freund, Carl M Zipser

Abstract readSystematic Review
In one paragraph

Synthesis in Spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guichande DuarteDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID 0009-0007-1178-6765
Markus HuppDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
José SpirigUniversity Spine Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Mazda FarshadUniversity Spine Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Martin SchubertDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Armin CurtDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Patrick FreundDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Carl M ZipserDepartment of Neurology and Neurophysiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4396-4796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic literature review.

objectiveUpdate on diagnostic utility of electrophysiology in lumbar spinal canal stenosis (LSCS). SUMMARY OF

backgroundLSCS is a highly prevalent degenerative spine condition characterized by neurogenic claudication, radicular pain, and muscle weakness. While lumbar spine MRI is the imaging modality for detecting spinal canal narrowing, it correlates poorly with clinical symptoms. Electrophysiological methods, including electromyography (EMG), nerve conduction studies (NCS), and evoked potentials (MEP and SEP), may provide complementary information on neural dysfunction. Current guidelines support paraspinal electromyography (EMG) mapping for symptomatic patients with imaging confirmed stenosis (grade B). In contrast, the diagnostic value of other electrophysiologic tests in LSCS remains uncertain.

methodsA systematic literature search was conducted in Medline and Embase for original studies on LSCS between 2020 and 2024. Two independent reviewers screened studies for inclusion. The extracted data was synthesized qualitatively. Study quality was assessed using the Robins-V2 tool. PROSPERO registration (CRD42024622427).

resultsThirteen studies met the inclusion criteria; study quality was moderate. Needle EMG of the limbs was evaluated in 23% of studies to detect denervation as a sign of radiculopathy. Twenty-three percent of the studies examined tibial nerve SEP or cauda equina MEP conduction time for lesion localization, with varying findings and utility for diagnosing LSCS. Surface EMG was investigated in 31% of studies and revealed significantly altered muscle activation patterns and compensatory gait adaptations in LSCS.

conclusionThere is an increasing number of studies combining surface EMG with gait assessments and tasks. This approach is interesting for being noninvasive, with clinical utility to be further determined. On the basis of previous guidelines, paraspinal mapping is considered the gold-standard electrophysiological diagnostic tool. Interestingly, there were no recent studies on paraspinal mapping, indicating a shift to alternative methods.

Indexed as

ElectromyographyLumbar VertebraeSpinal StenosisElectrodiagnosisEvoked PotentialsHumansNeural Conductionelectromyographygait assessmentslumbar spinal canal stenosisneurophysiology

Identifiers

PMID41379086
PMCPMC12928778

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.