Evidence map›Paper›PMID 41378825›Full record

ArticleThe Journal of infectious diseases2026

Chronic Malaria Is Associated With Trauma-related Splenic Rupture Requiring Splenectomy.

Putu A I Shanti, King Alexander, Freis Candrawati, Benediktus Andries, Noy Norman Kambuaya, Hasrini Rini, Aisah R Amelia, Agatha M Puspitasari, Ristya Amalia, Desandra A Rahmayenti and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Putu A I ShantiSurgery Department, Mimika District Hospital, Timika, Papua, Indonesia.
King AlexanderSurgery Department, Mimika District Hospital, Timika, Papua, Indonesia.
Freis CandrawatiPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Benediktus AndriesPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Noy Norman KambuayaPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.ORCID 0009-0008-6191-5710
Hasrini RiniPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Aisah R AmeliaExeins Health Initiative, Malaria Pathogenesis, Jakarta, Indonesia.ORCID 0009-0009-9341-7692
Agatha M PuspitasariExeins Health Initiative, Malaria Pathogenesis, Jakarta, Indonesia.
Ristya AmaliaExeins Health Initiative, Malaria Pathogenesis, Jakarta, Indonesia.
Desandra A RahmayentiPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Leo LeonardoPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Pak PrayogaPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.
Leily TriantyEijkman Research Centre for Molecular Biology, BRIN, Cibinong, Indonesia.ORCID 0000-0002-4368-476X
Zuleima PavaMenzies School of Health Research and Charles Darwin University, Global and Tropical Health Division, Darwin, Northern Territory, Australia.ORCID 0000-0002-4802-0647
Enny KenangalemPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.ORCID 0000-0002-0481-7435
Sarah AuburnMenzies School of Health Research and Charles Darwin University, Global and Tropical Health Division, Darwin, Northern Territory, Australia.
Ric N PriceMenzies School of Health Research and Charles Darwin University, Global and Tropical Health Division, Darwin, Northern Territory, Australia.ORCID 0000-0003-2000-2874
Ida Safitri LaksanawatiCentre for Child Health-PRO, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Pierre A BuffetInstitut Pasteur, University of Paris, Paris, France.
Rintis NoviyantiEijkman Research Centre for Molecular Biology, BRIN, Cibinong, Indonesia.ORCID 0000-0003-1383-3274
Nicholas M AnsteyMenzies School of Health Research and Charles Darwin University, Global and Tropical Health Division, Darwin, Northern Territory, Australia.
Jeanne R PoespoprodjoPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.ORCID 0000-0003-1573-734X
Steven KhoPapuan Health and Community Development Foundation, Timika Laboratory Facility, Timika, Papua, Indonesia.ORCID 0000-0003-0926-8049

Funding

Australian Centre of Research Excellence in Malaria EliminationAustralian Department of Foreign Affairs and TradeAustralian Government Postgraduate Award ScholarshipAustralian National Health and Medical Research Council 1037304Australian National Health and Medical Research Council 1042072Australian National Health and Medical Research Council 1131932Australian National Health and Medical Research Council 1135820Australian National Health and Medical Research Council 2008501Australian National Health and Medical Research Council 2025376Australian National Health and Medical Research Council 2025377French National Research Agency ANR-24-CE17-2900-01Idex Université Paris Cité ANR-18-IDEX-0001Improving Health Outcomes in the Tropical NorthNIH HHSWellcome Trust 099875
6 · The paper itself

Abstract

Splenic rupture is a recognized complication of acute Plasmodium falciparum and Plasmodium vivax malaria, but the risk of splenic rupture in chronic asymptomatic infections is unknown. In Timika, Papua, Indonesia, we determined the proportion of PCR-detectable asymptomatic peripheral parasitemia in patients undergoing trauma-related splenectomy (2015-21) and found it was more than twice the proportion compared to a 2013 household survey of the general population (87.9% [29/33] vs 38.6% [697/1807]; P < .0001). Our findings suggest asymptomatic parasitemia with either P. falciparum or P. vivax is associated with splenic rupture following trauma, pointing toward an additional consequence of chronic infection in malaria-endemic areas.

Indexed as

Malaria, FalciparumMalaria, VivaxSplenectomySplenic RuptureWounds and InjuriesAdolescentAdultAgedChronic DiseaseFemaleHumansIndonesiaMaleMiddle AgedParasitemiaPlasmodium falciparumchronic asymptomatic malariaspleen rupturesplenectomytrauma

Identifiers

PMID41378825
PMCPMC13017132

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.